Thienprasit P, Bantli H, Bloedel J R, Chou S N
J Neurosurg. 1975 Feb;42(2):150-4. doi: 10.3171/jns.1975.42.2.0150.
The authors report studies indicating that delayed local cooling is effective in minimizing the neurological deficits of experimental spinal cord injury in cats. Cortical evoked responses were useful in predicting the neurological outcome; untreated animals whose evoked response disappeared for 6 hours failed to recover whereas all treated animals in the same group recovered dramatically. Decompression by laminectomy alone proved ineffective. Possible explanations for the therapeutic effects of cooling and the significance of the delay are briefly discussed.
作者报告的研究表明，延迟局部降温对于将猫实验性脊髓损伤的神经功能缺损降至最低有效。皮质诱发反应有助于预测神经学结果；诱发反应消失6小时的未治疗动物未能恢复，而同一组中所有接受治疗的动物都显著恢复。仅通过椎板切除术减压被证明无效。文中简要讨论了降温治疗效果的可能解释以及延迟的意义。
