Suppr超能文献

关键点:愈合某些伤口所需的不仅仅是时间。

Checkpoints: it takes more than time to heal some wounds.

作者信息

Rhind N, Russell P

机构信息

The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

出版信息

Curr Biol. 2000;10(24):R908-11. doi: 10.1016/s0960-9822(00)00849-6.

Abstract

The S-phase DNA damage checkpoint seems to provide a twist on the checkpoint theme. Instead of delaying replication and allowing repair as a consequence, it may activate repair and delay replication as a consequence.

摘要

S期DNA损伤检查点似乎为检查点机制带来了新变化。它并非延迟复制并因此允许修复,而是可能会激活修复并因此延迟复制。

相似文献

1
Checkpoints: it takes more than time to heal some wounds.
Curr Biol. 2000;10(24):R908-11. doi: 10.1016/s0960-9822(00)00849-6.
2
The Mre11 complex and ATM: collaborating to navigate S phase.
Curr Opin Cell Biol. 2000 Jun;12(3):293-6. doi: 10.1016/s0955-0674(00)00091-0.
4
ATM and ATR: networking cellular responses to DNA damage.
Curr Opin Genet Dev. 2001 Feb;11(1):71-7. doi: 10.1016/s0959-437x(00)00159-3.
5
An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage.
Mol Cell Biol. 2002 Dec;22(24):8552-61. doi: 10.1128/MCB.22.24.8552-8561.2002.
6
Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway.
Mol Cell Biol. 2004 Nov;24(22):10016-25. doi: 10.1128/MCB.24.22.10016-10025.2004.
7
DNA repair: how to PIKK a partner.
Curr Biol. 2005 Jun 21;15(12):R473-5. doi: 10.1016/j.cub.2005.06.012.
8
Cell-cycle checkpoint kinases: checking in on the cell cycle.
Curr Opin Cell Biol. 2000 Dec;12(6):697-704. doi: 10.1016/s0955-0674(00)00154-x.
9
ATR/Mec1: coordinating fork stability and repair.
Curr Opin Cell Biol. 2009 Apr;21(2):237-44. doi: 10.1016/j.ceb.2009.01.017. Epub 2009 Feb 21.
10
A DNA damage response pathway controlled by Tel1 and the Mre11 complex.
Mol Cell. 2001 Jun;7(6):1255-66. doi: 10.1016/s1097-2765(01)00270-2.

引用本文的文献

1
DNA Damage: From Threat to Treatment.
Cells. 2020 Jul 10;9(7):1665. doi: 10.3390/cells9071665.
2
Replication Stress and Consequential Instability of the Genome and Epigenome.
Molecules. 2019 Oct 27;24(21):3870. doi: 10.3390/molecules24213870.
4
The Emerging Role of GLP-1 Receptors in DNA Repair: Implications in Neurological Disorders.
Int J Mol Sci. 2017 Aug 26;18(9):1861. doi: 10.3390/ijms18091861.
5
Replication fork slowing and stalling are distinct, checkpoint-independent consequences of replicating damaged DNA.
PLoS Genet. 2017 Aug 14;13(8):e1006958. doi: 10.1371/journal.pgen.1006958. eCollection 2017 Aug.
7
Checkpoint regulation of replication forks: global or local?
Biochem Soc Trans. 2013 Dec;41(6):1701-5. doi: 10.1042/BST20130197.
8
The Saccharomyces cerevisiae F-box protein Dia2 is a mediator of S-phase checkpoint recovery from DNA damage.
Genetics. 2013 Feb;193(2):483-99. doi: 10.1534/genetics.112.146373. Epub 2012 Nov 19.
9
Cyclin-C-dependent cell-cycle entry is required for activation of non-homologous end joining DNA repair in postmitotic neurons.
Cell Death Differ. 2010 Jul;17(7):1189-98. doi: 10.1038/cdd.2009.221. Epub 2010 Jan 29.
10
Regulation of DNA replication by the S-phase DNA damage checkpoint.
Cell Div. 2009 Jul 3;4:13. doi: 10.1186/1747-1028-4-13.

本文引用的文献

1
Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1.
Mol Cell Biol. 2000 Dec;20(23):8758-66. doi: 10.1128/MCB.20.23.8758-8766.2000.
3
DNA damage checkpoints and DNA replication controls in Saccharomyces cerevisiae.
Mutat Res. 2000 Jun 30;451(1-2):187-96. doi: 10.1016/s0027-5107(00)00049-x.
4
RecQ-like helicases: the DNA replication checkpoint connection.
J Cell Sci. 2000 Aug;113 ( Pt 15):2641-6. doi: 10.1242/jcs.113.15.2641.
5
The Bloom's syndrome gene product promotes branch migration of holliday junctions.
Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6504-8. doi: 10.1073/pnas.100448097.
6
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway.
Nature. 2000 Apr 6;404(6778):613-7. doi: 10.1038/35007091.
8
10
The effects of ionizing radiation on DNA synthesis in eukaryotic cells.
Int J Radiat Biol. 1999 Mar;75(3):267-83. doi: 10.1080/095530099140456.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验