Rhind N, Russell P
The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Curr Biol. 2000;10(24):R908-11. doi: 10.1016/s0960-9822(00)00849-6.
The S-phase DNA damage checkpoint seems to provide a twist on the checkpoint theme. Instead of delaying replication and allowing repair as a consequence, it may activate repair and delay replication as a consequence.
S期DNA损伤检查点似乎为检查点机制带来了新变化。它并非延迟复制并因此允许修复,而是可能会激活修复并因此延迟复制。