Krüsmann W, Slanina J, Vorwerck H
Strahlentherapie. 1979 Jun;155(6):416-8.
Phytohemagglutinin-stimulated DNA-synthesis of lymphocytes was measured in 35 patients with Hodgkin's disease in continuous remission 1 to 8 years after intensive high-energy radiotherapy. In comparison to a normal control group we found there was no significant difference between the values of patients in complete remission and healthy subjects. We conclude that the extremely suppressed lymphocytic reactivity as measured by DNA-synthesis during irradiation may again reach normal values one or two years after radiotherapy.
在35例霍奇金病患者中,于高能强化放疗后持续缓解1至8年,检测了植物血凝素刺激的淋巴细胞DNA合成。与正常对照组相比,我们发现完全缓解患者的值与健康受试者的值之间无显著差异。我们得出结论,放疗期间通过DNA合成测量的淋巴细胞反应性极度受抑制,在放疗后一两年可能再次恢复到正常水平。