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霍奇金病扩大放疗后淋巴细胞对植物血凝素刺激的反应(作者译)

[Lymphocyte response to phytohemagglutinin-stimulation after extended radiation therapy in Hodgkin's disease (author's transl)].

作者信息

Krüsmann W, Slanina J, Vorwerck H

出版信息

Strahlentherapie. 1979 Jun;155(6):416-8.

PMID:111376
Abstract

Phytohemagglutinin-stimulated DNA-synthesis of lymphocytes was measured in 35 patients with Hodgkin's disease in continuous remission 1 to 8 years after intensive high-energy radiotherapy. In comparison to a normal control group we found there was no significant difference between the values of patients in complete remission and healthy subjects. We conclude that the extremely suppressed lymphocytic reactivity as measured by DNA-synthesis during irradiation may again reach normal values one or two years after radiotherapy.

摘要

在35例霍奇金病患者中,于高能强化放疗后持续缓解1至8年,检测了植物血凝素刺激的淋巴细胞DNA合成。与正常对照组相比,我们发现完全缓解患者的值与健康受试者的值之间无显著差异。我们得出结论,放疗期间通过DNA合成测量的淋巴细胞反应性极度受抑制,在放疗后一两年可能再次恢复到正常水平。

相似文献

1
[Lymphocyte response to phytohemagglutinin-stimulation after extended radiation therapy in Hodgkin's disease (author's transl)].霍奇金病扩大放疗后淋巴细胞对植物血凝素刺激的反应(作者译)
Strahlentherapie. 1979 Jun;155(6):416-8.
2
Distinguishing features of the immunology of Hodgkin's disease in children.儿童霍奇金淋巴瘤免疫学的显著特征。
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Hodgkin's disease. Results from a program in radiation therapy.霍奇金淋巴瘤。放射治疗项目的结果。
Am J Clin Oncol. 1984 Apr;7(2):159-71.
4
[Hodgkin's disease. T lymphocyte defect in patients in complete remission (author's transl)].[霍奇金病。完全缓解患者的T淋巴细胞缺陷(作者译)]
Pathol Biol (Paris). 1978 Mar-Apr;26(3-4):159-62.
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Prognostic factors in Hodgkin's disease. II. Role of the lymphocyte defect.霍奇金病的预后因素。II. 淋巴细胞缺陷的作用。
Scand J Haematol. 1978 Apr;20(4):306-18.
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[Comments about use of polychemotherapy MOPP associated with radiotherapy in the treatment of early stages of Hodgkin's disease. Preliminary report of 58 patients (author's transl)].
Ann Med Interne (Paris). 1980;131(4):239-43.
7
Persisting lymphocyte deficiences during remission in Hodgkin's disease.霍奇金淋巴瘤缓解期持续存在的淋巴细胞缺陷
Clin Exp Immunol. 1977 Jun;28(3):389-93.
8
[Hodgkin's disease. T lymphocyte defect in patients in complete remission (author's transl)].[霍奇金病。完全缓解患者的T淋巴细胞缺陷(作者译)]
Sem Hop. 1978;54(37-40):1155-8.
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[Changes in concentrations of IgM, IgA and IgM immune globulins after megavolt therapy with the large-field technic in patients with Hodgkin's disease].[霍奇金病患者采用大野技术进行兆伏治疗后 IgM、IgA 和 IgM 免疫球蛋白浓度的变化]
Strahlenther Onkol. 1988 Jun;164(6):323-9.
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Impaired lymphocyte function in untreated Hodgkin's disease.未经治疗的霍奇金淋巴瘤患者淋巴细胞功能受损。
N Engl J Med. 1974 Jan 24;290(4):181-6. doi: 10.1056/NEJM197401242900402.