Benington P C, Gillgrass T J, Foye R H, Millett D T, Gilmour W H
Unit of Orthodontics, Glasgow Dental Hospital and School, 378 Sauchiehall Street, G2 3JZ, Glasgow, UK.
J Dent. 2001 Jan;29(1):23-9. doi: 10.1016/s0300-5712(00)00034-8.
To determine firstly, if sustained fluoride release can be achieved from five orthodontic adhesives: Ketac-Cem, Fuji ORTHO LC, Sequence, Transbond and Right-On, with daily exposure to fluoride mouthrinse in vitro, and secondly, if sustained fluoride release can be re-established from the same specimens, after an interruption in mouthrinse exposure.
Ten brackets were bonded to bovine incisors using each adhesive. Each adhesive group was divided equally into a test and a control sub-group. In phase 1 (42 days), the test sub-groups were exposed for 1min daily to fluoride mouthrinse (225 ppm), followed by immersion in de-ionised water for 42 days to deplete their fluoride reserves. Mouthrinse exposure was then resumed in phase 2 (28 days). Mean cumulative fluoride release (MCFR) was calculated for days 0-21 of phase 1 and for the plateau portion of the fluoride release curves in phase 1 (days 21-42) and phase 2 (days 7-28).
During phase 1, the MCFR for each test sub-group was significantly greater than its control (p<0.05). There was no significant difference in MCFR between the curve plateau portion of phases 1 and 2 for all adhesives except Transbond, for which MCFR was less in phase 2 (p<0. 05).
Sustained fluoride release occurred for each adhesive exposed daily to fluoride mouthrinse, at a level significantly greater than its control. After fluoride exhaustion, re-exposure to daily fluoride mouthrinse produced sustained fluoride release levels comparable to those prior to exhaustion, for all adhesives except Transbond.
首先确定在体外每日接触含氟漱口水的情况下,五种正畸粘合剂(Ketac-Cem、Fuji ORTHO LC、Sequence、Transbond和Right-On)是否能实现持续的氟释放;其次确定在中断漱口水接触后,相同样本是否能重新建立持续的氟释放。
使用每种粘合剂将十个托槽粘结到牛切牙上。每个粘合剂组平均分为一个测试亚组和一个对照亚组。在第1阶段(42天),测试亚组每天暴露于含氟漱口水(225 ppm)1分钟,然后浸泡在去离子水中42天以耗尽其氟储备。然后在第2阶段(28天)恢复漱口水暴露。计算第1阶段0至21天以及第1阶段(21至42天)和第2阶段(7至28天)氟释放曲线平稳部分的平均累积氟释放量(MCFR)。
在第1阶段,每个测试亚组的MCFR均显著高于其对照组(p<0.05)。除Transbond外,所有粘合剂在第1阶段和第2阶段曲线平稳部分的MCFR无显著差异,Transbond在第2阶段的MCFR较低(p<0.05)。
每日接触含氟漱口水的每种粘合剂均出现持续的氟释放,且释放水平显著高于其对照组。在氟耗尽后,重新每日接触含氟漱口水,除Transbond外,所有粘合剂产生的持续氟释放水平与耗尽前相当。