Kuklin A, Shams S, Shah S
BioDiscovery Inc., Los Angeles, CA 9006, USA.
Genetica. 2000;108(1):41-6. doi: 10.1023/a:1004087525565.
This paper focuses on microarray image analysis and discusses a completely automated approach to image processing, which eliminates human intervention. A system for automated image processing is described, which is capable of processing image files in a batch-mode thus allowing high-throughput of microarray image analysis. Grid-placement and spot finding are achieved without operator's help. The software eliminates noise signals from the data analysis process and minimizes operator's involvement in the procedure.