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子代出生尺寸、早产与母亲死亡率

Birth dimensions of offspring, premature birth, and the mortality of mothers.

作者信息

Smith G D, Whitley E, Gissler M, Hemminki E

出版信息

Lancet. 2000 Dec 16;356(9247):2066-7. doi: 10.1016/S0140-6736(00)03406-1.

DOI:10.1016/S0140-6736(00)03406-1
PMID:11145495
Abstract

A person's birthweight is inversely related to their cardiovascular disease (CVD) mortality risk, and preliminary data suggest that the birthweights of offspring are also inversely related to parental CVD mortality risk. In a cohort of pregnant Finnish women, we assessed the relation between birth dimensions of the offspring and maternal characteristics, and subsequent mortality. Maternal CVD mortality was inversely related to the birthweight of offspring and women having premature deliveries were also at increased CVD risk. Breast-cancer mortality was positively associated with ponderal index of offspring.

摘要

一个人的出生体重与心血管疾病(CVD)死亡风险呈负相关,初步数据表明,后代的出生体重也与父母的CVD死亡风险呈负相关。在一组芬兰孕妇中,我们评估了后代出生尺寸与母亲特征以及随后死亡率之间的关系。母亲的CVD死亡率与后代的出生体重呈负相关,早产的女性患CVD的风险也会增加。乳腺癌死亡率与后代的 ponderal 指数呈正相关。

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