Fitzgerald M J, Coleman L T
Radiology Department, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia.
Pediatr Radiol. 2000 Dec;30(12):861-5. doi: 10.1007/s002470000346.
Myelinoclastic diffuse sclerosis (MDS, Schilder's disease) is a rare CNS demyelinating disorder affecting mainly children and usually presenting as an intracranial mass lesion. We report the first case of recurrent intracranial MDS where the third episode of demyelination involved the cervical spinal cord. This may represent a subset of the disease, which should be considered as Schilder's variant (childhood form) of multiple sclerosis.
髓鞘破坏型弥漫性硬化（MDS，希尔德病）是一种罕见的中枢神经系统脱髓鞘疾病，主要影响儿童，通常表现为颅内肿块病变。我们报告了首例复发性颅内MDS病例，其中第三次脱髓鞘发作累及颈髓。这可能代表了该疾病的一个亚型，应被视为多发性硬化的希尔德变异型（儿童型）。
