Behnia M, Clay A S, Farber M O
Am J Med Sci. 2000 Dec;320(6):368-73. doi: 10.1097/00000441-200012000-00003.
Respiratory failure in myxedema is a complex medical emergency and may require prolonged ventilatory assistance. Appropriate management of this medical problem requires an understanding of its effects on the central nervous system and peripheral neuromusculoskeletal system. Weaning of these patients can be very protracted and requires a diligent multidisciplinary approach. Because of its infrequency, ventilatory management of severe hypothyroidism has not been studied in a controlled fashion. The first part of this review discusses the mechanisms of respiratory failure in myxedema. The second part explores strategies in mechanical ventilation and weaning of myxedematous patients.
黏液性水肿所致呼吸衰竭是一种复杂的医疗急症，可能需要长期通气支持。妥善处理这一医疗问题需要了解其对中枢神经系统和外周神经肌肉骨骼系统的影响。这些患者的撤机过程可能非常漫长，需要多学科的精心协作。由于其发病率较低，尚未对严重甲状腺功能减退的通气管理进行对照研究。本综述的第一部分讨论黏液性水肿呼吸衰竭的机制。第二部分探讨黏液性水肿患者机械通气及撤机的策略。
