Department of Intensive Care Medicine (632), Radboud University Nijmegen Medical Centre, Postbox 9101, 6500 HB Nijmegen, The Netherlands.
Crit Care. 2010;14(6):245. doi: 10.1186/cc9296. Epub 2010 Dec 8.
About 20% to 30% of patients are difficult to wean from invasive mechanical ventilation. The pathophysiology of difficult weaning is complex. Accordingly, determining the reason for difficult weaning and subsequently developing a treatment strategy require a dedicated clinician with in-depth knowledge of the pathophysiology of weaning failure. This review presents a structural framework ('ABCDE') for the assessment and treatment of difficult-to-wean patients. Earlier recognition of the underlying causes may expedite weaning from mechanical ventilation.
大约 20%至 30%的患者难以从有创机械通气中撤机。撤机困难的病理生理学较为复杂。因此，确定撤机困难的原因并随后制定治疗策略需要由对撤机失败的病理生理学有深入了解的临床医生来进行。本篇综述提出了一种评估和治疗撤机困难患者的结构性框架（“ABCDE”）。更早识别潜在病因可能有助于加快机械通气的撤机过程。
