Euscher E, Vaswani K, Frankel W
Departments of Pathology and Radiology, Ohio State University, Columbia, OH 43210, USA.
Ann Diagn Pathol. 2000 Dec;4(6):379-85. doi: 10.1053/adpa.2000.19371.
Eosinophilic pancreatitis is a rare disorder that is frequently diagnosed only after pancreatic resection for suspected pancreatic tumor. It typically occurs in the setting of either eosinophilic gastroenteritis or the hypereosinophilic syndrome. Isolated eosinophilic infiltration of the pancreas is less common. We describe a case of a 36-year-old man who presented with the clinical symptoms of acute pancreatitis. Radiologic evaluation revealed an obstructive pancreatic lesion suspicious for carcinoma. Pathologic examination of the resection specimen revealed a dense infiltrate of eosinophils in the pancreas. Although an uncommon condition, eosinophilic pancreatitis is a syndrome lacking well-defined causes that can be associated with eosinophilic gastroenteritis, a treatable condition, or the potentially fatal hypereosinophilic syndrome. While the radiographic features of this condition can vary widely, eosinophilic infiltration of the pancreas with or without involvement of the gastrointestinal tract is the pathologic feature common to all of the previously reported cases.
嗜酸性胰腺炎是一种罕见的疾病，通常仅在因疑似胰腺肿瘤进行胰腺切除术后才得以诊断。它通常发生在嗜酸性胃肠炎或高嗜酸性粒细胞综合征的背景下。胰腺孤立性嗜酸性浸润较少见。我们描述了一例36岁男性，他表现出急性胰腺炎的临床症状。影像学评估显示有一个疑似癌的阻塞性胰腺病变。切除标本的病理检查显示胰腺中有密集的嗜酸性粒细胞浸润。尽管嗜酸性胰腺炎并不常见，但它是一种病因不明的综合征，可与嗜酸性胃肠炎（一种可治疗的疾病）或潜在致命的高嗜酸性粒细胞综合征相关。虽然这种疾病的影像学特征差异很大，但胰腺嗜酸性浸润无论是否累及胃肠道都是所有先前报道病例共有的病理特征。
