di Bella P, Calisto M L, Calimeri S, Squeri R, Anzalone C, Lo Giudice D, Bramanti P
Department of Hygiene, Preventive Medicine and Public Health, University of Messina.
Acta Neurol (Napoli). 1993 Aug;15(4):253-7.
The authors evaluate the presence of anti-Borrelia burgdorferi antibodies in a group of polysclerotic patients of Eastern Sicily, in order to verify or dismiss a correlation between Borrelia infection and demyelinizing syndrome. 460 samples of serum were examined, of which 60 belonged to patients affected by definite multiple sclerosis; the other 400 were taken from a group of apparently healthy subjects. From the analysis of the data obtained it can be seen that of the 60 polysclerotic subjects examined, 12 equal to 20% were found to be positive for the presence of IgG anti-Borrelia burgdorferi, while in the control group 30 subjects were found to be positive, equal 7.5%.
作者评估了西西里岛东部一组多硬化症患者体内抗伯氏疏螺旋体抗体的存在情况，以验证或排除伯氏疏螺旋体感染与脱髓鞘综合征之间的关联。检测了460份血清样本，其中60份来自确诊为多发性硬化症的患者；另外400份取自一组看似健康的受试者。从所获数据的分析中可以看出，在检测的60名多硬化症受试者中，有12名（占20%）被发现抗伯氏疏螺旋体IgG呈阳性，而在对照组中，有30名受试者呈阳性，占7.5%。
