Suga K
Department of Radiology, Jikei University School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 2000 Oct;60(12):684-90.
This paper describes some of the basic pathophysiologic information required for the interpretation of pulmonary perfusion and ventilation scintigraphy, i.e., perfusion reduction associated with hypoxic vasoconstriction due to ventilatory dysfunction, vascular beds in the upper lung as a reserve of perfusion, stripe sign, fissure sign, characteristic MAA distributions in right-to-left shunt, and different tracer distributions in the lung according to tracer sizes. The utility of perfusion and xenon-133 SPECT in the evaluation of cross-sectional lung function in various disorders is also emphasized. Also described are the utility of Tc-99m-DTPA lung scan in the evaluation of alveolar permeability, Ga-67 scan in the diagnosis of sarcoidosis, bone scans in the diagnosis of pulmonary metastatic calcifications and stress rib fractures, lymphoscintigraphy in the diagnosis of chylothorax, and Tc-99m-HSA scan in the detection of bleeding sites.
本文描述了解读肺灌注和通气闪烁扫描所需的一些基本病理生理信息，即由于通气功能障碍导致的与低氧性血管收缩相关的灌注减少、作为灌注储备的上肺血管床、条纹征、裂沟征、右向左分流中特征性的大颗粒聚合白蛋白（MAA）分布以及根据示踪剂大小在肺内不同的示踪剂分布。还强调了灌注和氙-133单光子发射计算机断层扫描（SPECT）在评估各种疾病的肺横断面功能中的作用。此外还描述了锝-99m-二乙三胺五乙酸（Tc-99m-DTPA）肺扫描在评估肺泡通透性中的作用、镓-67扫描在结节病诊断中的作用、骨扫描在肺转移性钙化和应力性肋骨骨折诊断中的作用、淋巴闪烁扫描在乳糜胸诊断中的作用以及锝-99m-人血清白蛋白（Tc-99m-HSA）扫描在出血部位检测中的作用。
