Kawakami K
Department of Radiology, Jikei University School of Medicine, Tokyo, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Dec;32 Suppl:223-30.
Radionuclide study provides many kinds of information in patients with pulmonary diseases. These include ventilation (V) perfusion (Q), distribution of inhaled therapeutic aerosols, mucociliary movement, epithelial permeability, and tumor imaging. VQ scintigraphy can be used in cases of pulmonary embolism, obstructive pulmonary diseases, and A-V shunt. 99mTc-technegas is useful in the study of ventilation, and many reports have been published about this new radiopharmaceutical. 67Ga scintigraphy can be used to evaluate patients with interstitial pulmonary diseases. Measurement of epithelial permeability with 99mTc-DTPA is also useful to assess damaged lung epithelium. For tumor imaging, 201T1C1 is be coming popular for the diagnosis of lung cancer and for early detection of metastatic lesions. Tumor detection with 99mTc-MIBI is also used to try to differentiate malignant tumors from benign processes.
放射性核素研究可为肺部疾病患者提供多种信息。这些信息包括通气（V）、灌注（Q）、吸入治疗性气溶胶的分布、黏液纤毛运动、上皮通透性以及肿瘤显像。VQ闪烁扫描可用于肺栓塞、阻塞性肺部疾病和动静脉分流的病例。99mTc-锝气体对通气研究很有用，关于这种新型放射性药物已经发表了许多报告。67Ga闪烁扫描可用于评估间质性肺部疾病患者。用99mTc-DTPA测量上皮通透性也有助于评估受损的肺上皮。对于肿瘤显像，201TlCl在肺癌诊断和转移灶的早期检测中正变得越来越普遍。用99mTc-MIBI进行肿瘤检测也用于尝试区分恶性肿瘤和良性病变。
