先天性输精管缺如男性中精子抗体的低发生率。

Low incidence of sperm antibodies in men with congenital absence of the vas deferens.

作者信息

Patrizio P, Moretti-Rojas I, Ord T, Balmaceda J, Silber S, Asch R H

机构信息

Department of Obstetrics and Gynecology, University of California, Irvine, Orange 92663.

出版信息

Fertil Steril. 1989 Dec;52(6):1018-21. doi: 10.1016/s0015-0282(16)53168-9.

DOI:10.1016/s0015-0282(16)53168-9

PMID:2591559

Abstract

The incidence of antisperm antibodies in serum and seminal fluid of 27 azoospermic men with congenital absence of the vas deferens is evaluated. The presence of antisperm antibodies was assessed using the immunobead test, the agglutination test, and immobilization test. Five patients with vasovasostomy or vasoepididymostomy attempts were included in the study and tested for the presence of antisperm antibodies. Contrary to a previous report, a low incidence (11%) of antisperm antibodies has been found in patients with congenital absence of the vas. In agreement with previous studies, in five patients who had failed vasoepididymostomy or vasovasostomy, a high incidence (71%) of antisperm antibodies was found.

摘要

对27例先天性输精管缺如的无精子症男性血清和精液中的抗精子抗体发生率进行了评估。使用免疫珠试验、凝集试验和制动试验评估抗精子抗体的存在情况。5例尝试输精管吻合术或输精管附睾吻合术的患者被纳入研究，并检测抗精子抗体的存在情况。与之前的一份报告相反，在先天性输精管缺如的患者中发现抗精子抗体的发生率较低（11%）。与之前的研究一致，在5例输精管附睾吻合术或输精管吻合术失败的患者中，发现抗精子抗体的发生率较高（71%）。