Martín-Blanco E, Knust E
Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Cantoblanco, Madrid 28049, Spain.
Curr Biol. 2001 Jan 9;11(1):R28-31. doi: 10.1016/s0960-9822(00)00039-7.
Spreading and fusion of epithelial sheets are conserved morphogenetic mechanisms that help shape embryos and tissues. Recent findings suggest that the formation of dynamic filopodia at the leading front of the epithelia plays a critical role in regulating cell movement and recognition during these processes.
上皮细胞层的扩展和融合是保守的形态发生机制,有助于塑造胚胎和组织。最近的研究结果表明,上皮细胞前沿动态丝状伪足的形成在这些过程中调节细胞运动和识别方面起着关键作用。