Taylor H R, McCarty C A, Nanjan M B
Department of Ophthalmology, University of Melbourne, Centre for Eye Research Australia, Victoria, Australia.
Trans Am Ophthalmol Soc. 2000;98:91-6; discussion 96-9.
To describe predictors of mortality in the 5-year follow-up of the Melbourne Visual Impairment Project (VIP) cohort.
The Melbourne VIP was a population-based study of the distribution and determinants of age-related eye disease in a cluster random sample of Melbourne residents aged 40 years and older. Baseline examinations were conducted between 1992 and 1994. In 1997, 5-year follow-up examinations of the original cohort commenced. Causes of death were obtained from the National Death Index for all reported deaths.
Of the original 3,271 participants, 231 (7.1%) were reported to have died in the intervening 5 years. Of the remaining 3,040 participants eligible to return for follow-up examinations, 2,594 (85% of eligible) did participate, 51 (2%) had moved interstate or overseas, 83 (3%) could not be traced, and 312 (10%) refused to participate. Best corrected visual acuity < 6/12 and cortical cataract were associated with a significantly increased risk of mortality, as were increasing age, male sex, increased duration of cigarette smoking, increased duration of hypertension, and arthritis.
Even mild visual impairment increases the risk of death more than twofold.
描述墨尔本视力损害项目（VIP）队列5年随访中的死亡预测因素。
墨尔本VIP是一项基于人群的研究，对墨尔本40岁及以上居民的集群随机样本中年龄相关性眼病的分布和决定因素进行研究。1992年至1994年进行了基线检查。1997年，对原队列开始进行5年随访检查。所有报告死亡的死因均从国家死亡指数中获取。
在最初的3271名参与者中，有231人（7.1%）报告在这5年期间死亡。在其余有资格返回进行随访检查的3040名参与者中，2594人（符合条件者的85%）确实参与了，51人（2%）搬到了州际或海外，83人（3%）无法追踪到，312人（10%）拒绝参与。最佳矫正视力<6/12和皮质性白内障与死亡风险显著增加相关，年龄增加、男性、吸烟时间延长、高血压持续时间延长和关节炎也与死亡风险显著增加相关。
即使是轻度视力损害也会使死亡风险增加两倍以上。
