Lankin V S
Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, Novosibirsk.
Zh Vyssh Nerv Deiat Im I P Pavlova. 2000 Nov-Dec;50(6):1016-23.
The reaction of the hypothalamic-pituitary-adrenocortical axis (HPA) to social isolation from the herd was studied in 45 ewes of the Altaian breed at the age of 12, 16, and 27 months. The animals belonged to either "wild" or "domesticated" phenotypes which contrasted in the character of feeding and defensive responses to a human. The basal corticoid level in animals of both behavioral phenotypes was similar. The corticosteroid reaction was absent in animals with the "domesticated" type of behavior, while it was significantly pronounced in animals with a clear-cut behavioral reaction of withdrawal from a human ("wild" phenotype) at different ages. Sheep of the "wild" type of behavior were not uniform in the rate of the age-dependent decrease in withdrawal and stress reactions: these reactions were stable in individuals of "conservative" phenotypes. Thus, the ontogenetic formation of the long-term adaptation of the HPA axis of sheep to isolation depends on genetically determined behavior and factors, which control correlated changes in feeding and defensive reactions in animals of the "wild" phenotype.
对45只12、16和27月龄的阿尔泰品种母羊，研究了下丘脑 - 垂体 - 肾上腺皮质轴（HPA）对与群体隔离的反应。这些动物具有“野生”或“驯化”两种表型，在对人类的采食和防御反应特征上形成对比。两种行为表型动物的基础皮质激素水平相似。具有“驯化”行为类型的动物没有皮质类固醇反应，而在不同年龄对人类有明显行为退缩反应（“野生”表型）的动物中，皮质类固醇反应显著。“野生”行为类型的绵羊在退缩和应激反应随年龄下降的速率上并不一致：这些反应在“保守”表型的个体中较为稳定。因此，绵羊HPA轴对隔离的长期适应性的个体发育形成取决于基因决定的行为和因素，这些因素控制着“野生”表型动物采食和防御反应的相关变化。
