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[精神活性物质:基于1997年至1999年克拉科夫雅盖隆大学医学院临床毒理学系病例的分析]

[Psychoactive agents: an analysis based on cases from the Department of Clinical Toxicology College of Medicine of the Jagiellonian University in Kraków in the years 1997-1999].

作者信息

Pach J, Szkolnicka B, Targosz D, Radomska M

机构信息

Klinika Toksykologii KMPiChS, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.

出版信息

Przegl Lek. 2000;57(10):519-24.

Abstract

The aim of the study was to evaluate the frequency of acute poisoning with psychoactive substances in adult abusers of Kraków population in 1997, 1998 and 1999 and to compare the number of poisoned patients suffering withdrawal syndrome as predominant. 27.2% (n = 945) of all 3472 acute poisonings treated in the Department of Clinical Toxicology in 1997, 36.9% (n = 1193) of all 3236 treated in 1998 and 47.9% (n = 1546) of all 3233 treated cases that were acute poisoning with psychoactive substances among the abusers of Kraków adult population. Ethanol followed by narcotics in 1998, and by drugs coingested with ethanol and by narcotics in 1997 and 1999 was predominant psychoactive agent in all the analysed years. Organic solvents and glue sniffing and drug dependency increased again in 1999. Opiate derivatives produced at home from poppy straw or juice of poppy head were still the most common narcotic detected in body fluids, but decrease in number of acute opiates poisoning was noted in 1999 as compared to previous analysed years. The most of ethanol abusers aged from 30-49 years. The highest incidence of narcotic and drug dependency was noted in age between 20-29 years.

摘要

该研究的目的是评估1997年、1998年和1999年克拉科夫成年滥用药物者中精神活性物质急性中毒的发生率,并比较以戒断综合征为主的中毒患者数量。1997年临床毒理学部治疗的所有3472例急性中毒病例中,27.2%(n = 945)为精神活性物质急性中毒;1998年治疗的所有3236例病例中,36.9%(n = 1193)为精神活性物质急性中毒;1997年和1999年克拉科夫成年滥用药物者中,所有3233例急性中毒病例中,47.9%(n = 1546)为精神活性物质急性中毒。在所有分析年份中,主要的精神活性物质是乙醇,1998年其次是麻醉药品,1997年和1999年是与乙醇共同摄入的药物和麻醉药品。1999年有机溶剂、胶水吸入和药物依赖再次增加。从罂粟秆或罂粟头汁液在家自制的阿片类衍生物仍是体液中检测到的最常见麻醉药品,但与之前分析的年份相比,1999年急性阿片类中毒病例数量有所减少。大多数乙醇滥用者年龄在30 - 49岁之间。20 - 29岁年龄段的麻醉药品和药物依赖发生率最高。

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