外科患者的高胰高血糖素血症。
Hyperglucagonaemia in the surgical patient.
作者信息
Russell R C, Walker C J, Bloom S R
出版信息
Br Med J. 1975 Jan 4;1(5948):10-2. doi: 10.1136/bmj.1.5948.10.
Abstract
Twenty-one patients had serial samples of blood taken before, during, and after operation for the measurement of plasma glucagon, plasma insulin, and blood glucose concentrations. A significant rise in plasma glucagon level was noted during the operation. In contrast the plasma insulin concentration fell during the operation and rose in the postoperative period despite hyperglycaemia during and after the operation. These findings show that hyperglucagonaemia is a physiological consequence of a surgical operation and that the relationship of plasms glucagon to plasma insulin is complex.
摘要
21名患者在手术前、手术期间和手术后采集了系列血样，以测定血浆胰高血糖素、血浆胰岛素和血糖浓度。手术期间血浆胰高血糖素水平显著升高。相比之下，手术期间血浆胰岛素浓度下降，术后尽管手术期间及术后存在高血糖，但血浆胰岛素浓度仍升高。这些发现表明，高胰高血糖素血症是手术的生理后果，且血浆胰高血糖素与血浆胰岛素的关系很复杂。
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