早产双胞胎的呼吸窘迫综合征与出生顺序
Respiratory distress syndrome and birth order in premature twins.
作者信息
Hacking D, Watkins A, Fraser S, Wolfe R, Nolan T
机构信息
Department of Paediatrics, Mercy Hospital for Women, Clarendon Street, East Melbourne, Victoria 3002, Australia.
出版信息
Arch Dis Child Fetal Neonatal Ed. 2001 Mar;84(2):F117-21. doi: 10.1136/fn.84.2.f117.
Abstract
OBJECTIVE
To determine the effect of birth order on respiratory distress syndrome (RDS) in the outcome of twins in a large premature population managed in a modern neonatal intensive care unit.
METHODS
An historical cohort study design was used to analyse the neonatal outcomes of 301 premature liveborn twin sibling pairs of between 23 and 31 weeks gestation from the Australia and New Zealand Neonatal Network 1995 database.
RESULTS
Among the 56 twin sibling pairs who were discordant for RDS, the second twin was affected in 41 cases (odds ratio (OR) 2.7, 95% confidence interval (CI) 1.5 to 5.3). The excess risk of RDS in the second twin increased with gestation and was statistically significant for twins above 29 weeks gestation (OR 4.4, 95% CI 1.6 to 15).
CONCLUSIONS
There is a significant increased risk of RDS associated with being the second born of premature twins, which appears to depend on gestation.
摘要
目的
在现代新生儿重症监护病房管理的大量早产人群中，确定出生顺序对双胎结局中呼吸窘迫综合征（RDS）的影响。
方法
采用历史性队列研究设计，分析来自澳大利亚和新西兰新生儿网络1995年数据库中301对孕23至31周的早产活产双胞胎同胞对的新生儿结局。
结果
在56对RDS情况不一致的双胞胎同胞对中，41例第二胎受影响（比值比（OR）2.7，95%置信区间（CI）1.5至5.3）。第二胎患RDS的额外风险随孕周增加，对于孕周大于29周的双胞胎具有统计学意义（OR 4.4，95%CI 1.6至15）。
结论
早产双胞胎中第二胎患RDS的风险显著增加，这似乎取决于孕周。
相似文献
1
Respiratory distress syndrome and birth order in premature twins.早产双胞胎的呼吸窘迫综合征与出生顺序
Arch Dis Child Fetal Neonatal Ed. 2001 Mar;84(2):F117-21. doi: 10.1136/fn.84.2.f117.
2
Respiratory distress in heavier versus lighter twins.较重与较轻双胞胎的呼吸窘迫
J Perinat Med. 2001;29(1):60-3. doi: 10.1515/JPM.2001.008.
3
Determinants of perinatal mortality and serious neonatal morbidity in the second twin.第二个胎儿围产期死亡率及严重新生儿发病率的决定因素
Obstet Gynecol. 2006 Sep;108(3 Pt 1):556-64. doi: 10.1097/01.AOG.0000227747.37184.0a.
4
Birthweight discordance in twins and the risk of being heavier for respiratory distress syndrome.双胞胎出生体重不一致与呼吸窘迫综合征体重较重的风险
Twin Res Hum Genet. 2006 Oct;9(5):659-63. doi: 10.1375/183242706778553372.
5
The role of antenatal corticosteroids in twin pregnancies complicated by preterm birth.产前皮质类固醇在双胎妊娠合并早产中的作用。
Am J Obstet Gynecol. 2016 Oct;215(4):482.e1-9. doi: 10.1016/j.ajog.2016.05.037. Epub 2016 Jun 1.
6
Respiratory distress syndrome in twin infants compared with singletons.双胎婴儿与单胎婴儿相比的呼吸窘迫综合征。
Am J Obstet Gynecol. 2004 Jul;191(1):271-6. doi: 10.1016/j.ajog.2003.11.020.
7
Antenatal Corticosteroids for the Prevention of Respiratory Distress Syndrome in Premature Twins.产前使用皮质类固醇预防早产双胎呼吸窘迫综合征
Obstet Gynecol. 2016 Sep;128(3):583-91. doi: 10.1097/AOG.0000000000001577.
8
Respiratory morbidity in twins by birth order, gestational age and mode of delivery.按出生顺序、胎龄和分娩方式划分的双胞胎呼吸道发病率
J Perinat Med. 2016 Oct 1;44(8):899-902. doi: 10.1515/jpm-2015-0404.
9
Birth order and morbidity and mortality to hospital discharge among inborn very low-birthweight, very preterm twin infants admitted to neonatal intensive care: a retrospective cohort study.出生顺序与极低出生体重、极早早产双胎儿住院期间发病率和病死率的关系：一项回顾性队列研究。
Arch Dis Child Fetal Neonatal Ed. 2023 Jul;108(4):354-359. doi: 10.1136/archdischild-2022-324724. Epub 2022 Dec 30.
10
The Effect of Birth Order on Neonatal Morbidity and Mortality in Very Preterm Twins.出生顺序对极早产双胞胎新生儿发病率和死亡率的影响。
Am J Perinatol. 2017 Jul;34(9):845-850. doi: 10.1055/s-0037-1598255. Epub 2017 Feb 23.
引用本文的文献
1
Is There a Relationship Between Prenatal Dexamethasone and Postnatal Fructose Overexposure and Testicular Development, Function, and Oxidative Stress Parameters in Rats?产前地塞米松与产后果糖过度暴露以及大鼠睾丸发育、功能和氧化应激参数之间是否存在关联？
Int J Mol Sci. 2024 Dec 6;25(23):13112. doi: 10.3390/ijms252313112.
2
Clinical outcome and associated factors of respiratory distress syndrome among preterm neonates admitted to the neonatal intensive care unit of Adama Hospital and Medical College.阿达马医院与医学院新生儿重症监护病房收治的早产儿呼吸窘迫综合征的临床结局及相关因素
SAGE Open Med. 2022 Dec 25;10:20503121221146068. doi: 10.1177/20503121221146068. eCollection 2022.
3
Twin's Birth-Order Differences in Height and Body Mass Index From Birth to Old Age: A Pooled Study of 26 Twin Cohorts Participating in the CODATwins Project.从出生到老年双胞胎在身高和体重指数上的出生顺序差异：对参与CODATwins项目的26个双胞胎队列的汇总研究
Twin Res Hum Genet. 2016 Apr;19(2):112-24. doi: 10.1017/thg.2016.11.
4
Genetic Factors Contribute to Risk for Neonatal Respiratory Distress Syndrome among Moderately Preterm, Late Preterm, and Term Infants.遗传因素导致中度早产、晚期早产和足月儿患新生儿呼吸窘迫综合征的风险增加。
J Pediatr. 2016 May;172:69-74.e2. doi: 10.1016/j.jpeds.2016.01.031. Epub 2016 Feb 28.
5
Presenting Twins Are Exposed to Higher Levels of Inflammatory Mediators than Nonpresenting Twins as Early as the Midtrimester of Pregnancy.早在妊娠中期，与未出现的双胞胎相比，出现的双胞胎暴露于更高水平的炎症介质中。
PLoS One. 2015 Jun 15;10(6):e0125346. doi: 10.1371/journal.pone.0125346. eCollection 2015.
6
Prenatal programming of human neurological function.人类神经功能的产前编程
Int J Pept. 2011;2011:837596. doi: 10.1155/2011/837596. Epub 2011 Apr 5.
7
The genetic susceptibility to respiratory distress syndrome.遗传易感性与呼吸窘迫综合征。
Pediatr Res. 2009 Dec;66(6):693-7. doi: 10.1203/PDR.0b013e3181bbce86.
8
Evidence to support that spontaneous preterm labor is adaptive in nature: neonatal RDS is more common in "indicated" than in "spontaneous" preterm birth.支持自然早产具有适应性本质的证据：新生儿呼吸窘迫综合征在“引产”早产中比在“自然”早产中更常见。
J Perinat Med. 2009;37(1):53-8. doi: 10.1515/JPM.2009.036.
9
Effect of birth order on neonatal morbidity and mortality among very low birthweight twins: a population based study.极低出生体重双胞胎的出生顺序对新生儿发病率和死亡率的影响：一项基于人群的研究。
Arch Dis Child Fetal Neonatal Ed. 2004 Mar;89(2):F145-8. doi: 10.1136/adc.2002.021584.
本文引用的文献
1
TWIN PREGNANCY. INFLUENCE OF EARLY ADMISSION ON FETAL SURVIVAL.双胎妊娠。早期入院对胎儿存活的影响。
Obstet Gynecol. 1964 Jun;23:854-60.
2
TWIN ZYGOSITY AND PLACENTAL FORM IN RELATION TO THE OUTCOME OF PREGNANCY.
Am J Obstet Gynecol. 1963 Nov 1;87:566-77. doi: 10.1016/0002-9378(63)90050-4.
3
Australian national birthweight percentiles by gestational age.澳大利亚按孕周划分的全国出生体重百分位数。
Med J Aust. 1999 Feb 1;170(3):114-8. doi: 10.5694/j.1326-5377.1999.tb127678.x.
4
Neonatal outcome of very premature infants from multiple and singleton gestations.
Am J Obstet Gynecol. 1997 Sep;177(3):653-9. doi: 10.1016/s0002-9378(97)70160-1.
5
Morbidity and mortality of discordant twins up to 34 weeks of gestational age.孕龄达34周的不一致性双胎的发病率和死亡率。
Eur J Pediatr. 1996 Mar;155(3):224-9. doi: 10.1007/BF01953943.
6
Effects of birth order, gender, and intrauterine growth retardation on the outcome of very low birth weight in twins.出生顺序、性别及宫内生长迟缓对极低出生体重双胎结局的影响。
J Pediatr. 1993 Jul;123(1):132-6. doi: 10.1016/s0022-3476(05)81556-2.
7
The second-born twin: can we improve outcomes?第二出生的双胞胎：我们能改善其结局吗？
Am J Obstet Gynecol. 1994 Jun;170(6):1649-56; discussion 1656-7.
8
Effect of surfactant on morbidity, mortality, and resource use in newborn infants weighing 500 to 1500 g.
N Engl J Med. 1994 May 26;330(21):1476-80. doi: 10.1056/NEJM199405263302102.
9
Human fetal serum cortisol levels related to gestational age: evidence of a midgestational fall and a steep late gestational rise, independent of sex or mode of delivery.人类胎儿血清皮质醇水平与胎龄的关系：妊娠中期下降及妊娠晚期急剧上升的证据，与性别或分娩方式无关。
Am J Obstet Gynecol. 1982 Oct 1;144(3):276-82. doi: 10.1016/0002-9378(82)90579-8.
10
Is routine cesarean section necessary for vertex-breech and vertex-transverse twin gestations?头位-臀位和头位-横位双胎妊娠有必要常规剖宫产吗？
Am J Obstet Gynecol. 1984 Jan 1;148(1):1-5. doi: 10.1016/s0002-9378(84)80022-8.
Zotero 插件