Muszyński J, Siemińska J, Zagórowicz E, Górnicka B, Bogdańska M, Terebiński S, Tomi S
Department of Gastroenterology and Metabolic Diseases, Medical University, Warsaw, Poland.
Med Sci Monit. 2000 Mar-Apr;6(2):330-5.
148 patients with cholecystolithiasis and 77 patients with functional dyspepsia were examined to isolate symptoms or a syndrome characteristic of 'pure' (i.e. uncomplicated and without any co-existing diseases) cholecystolithiasis and functional dyspepsia; to evaluate their specificity and sensitivity as well as to estimate the power of each symptom or a group of symptoms to differentiate both these conditions. Endoscopy, ultrasound scan and biochemical tests were performed in each patient to exclude co-existence of any other gastrointestinal disorders. Also irritable bowel syndrome was excluded according to Manning's criteria. It was found that both these conditions have most often seven co-existing dyspeptic symptoms and that each symptom separately has low sensitivity and specificity for cholecystolithiasis as well as functional dyspepsia. The diagnostic power of each symptom is weak and even summing them up into groups of symptoms does not increase their diagnostic power.
对148例胆囊结石患者和77例功能性消化不良患者进行了检查，以分离出“单纯”（即未合并其他疾病且无并发症）胆囊结石和功能性消化不良的症状或综合征特征；评估其特异性和敏感性，并估计每种症状或一组症状区分这两种疾病的能力。对每位患者进行了内镜检查、超声扫描和生化检查，以排除其他胃肠道疾病的并存情况。此外，根据曼宁标准排除了肠易激综合征。结果发现，这两种疾病最常同时出现七种消化不良症状，且每种症状单独对胆囊结石和功能性消化不良的敏感性和特异性都较低。每种症状的诊断能力较弱，即使将它们归纳为症状组也不会增加其诊断能力。
