Rao K P, Gupta S, Jain A K, Agrawal A K, Gupta J P
Division of Gastroenterology, Banaras Hindu University, Varanasi.
J Assoc Physicians India. 1993 Jun;41(6):357-8, 363.
Six symptoms of Manning et al are widely used in clinical practice to diagnose irritable bowel syndrome (IBS). We studied 123 patients to evaluate the diagnostic value of Manning's criteria, using a preformed bowel symptom questionnaire which included these six symptoms. This study included 65 patients with IBS, 35 patients with non-ulcer dyspepsia, 23 patients with organic diseases of colon and 45 healthy controls. Sensitivity of presence of three or more symptoms of Manning's criteria discriminating irritable bowel syndrome from all other groups was 66.1%. Manning's criteria discriminated irritable bowel syndrome from organic diseases of colon with specificity and positive predictive value of 66.9% and 82.6%. When irritable bowel syndrome was compared with non-ulcer dyspepsia and healthy controls, specificities of Manning's criteria were 91.4% and 93.3% and positive predictive values 93.4% and 93.4% respectively.
曼宁等人提出的六种症状在临床实践中被广泛用于诊断肠易激综合征（IBS）。我们使用一份预先设计好的肠道症状问卷对123名患者进行研究，以评估曼宁标准的诊断价值，该问卷包含这六种症状。本研究包括65名肠易激综合征患者、35名非溃疡性消化不良患者、23名结肠器质性疾病患者和45名健康对照者。曼宁标准中出现三种或更多症状将肠易激综合征与所有其他组区分开来的敏感性为66.1%。曼宁标准将肠易激综合征与结肠器质性疾病区分开来，特异性和阳性预测值分别为66.9%和82.6%。当将肠易激综合征与非溃疡性消化不良和健康对照者进行比较时，曼宁标准的特异性分别为91.4%和93.3%，阳性预测值分别为93.4%和93.4%。
