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高效液相色谱中的印迹手性固定相。

Imprinted chiral stationary phases in high-performance liquid chromatography.

作者信息

Sellergren B

机构信息

Department of Inorganic Chemistry and Analytical Chemistry, Johannes Gutenberg University, Mainz, Germany.

出版信息

J Chromatogr A. 2001 Jan 12;906(1-2):227-52. doi: 10.1016/s0021-9673(00)00929-8.

DOI:10.1016/s0021-9673(00)00929-8
PMID:11215890
Abstract

Polymers imprinted with chiral templates offer a new generation of tailor-made chiral stationary phases (CSPs) with predictable selectivities. This review summarizes the present state of the art of molecular imprinting to generate tailor-made CSPs and provides an overview of the main factors involved in the manufacturing process that are crucial to the chromatographic performance of the phases.

摘要

用手性模板印迹的聚合物提供了新一代具有可预测选择性的定制手性固定相（CSPs）。本综述总结了用于生成定制CSPs的分子印迹技术的当前技术水平，并概述了制造过程中对固定相色谱性能至关重要的主要因素。

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