Antón García F, Guerola Lablanca J V, Catalán Macián J B, Barbas Galindo M J, Durà Navarro R, Richart Rufino M J
Centro de Salud Virgen de la Fuensanta, Valencia.
Aten Primaria. 2001 Jan;27(1):38-42. doi: 10.1016/s0212-6567(01)78771-9.
Main: to assess the change in coronary risk (CR) in adults after 8 years of their involvement in the Programme of Preventive Activities and Health Promotion (PAPPS). Secondary: to determine the level of anti-tetanus vaccination reached and patients' compliance with activities.
"Before and after" intervention study without random allocation.
A general medical clinic at a health centre.
429 patients (204 men, 225 women) between 30 and 65 monitored for 8 years, recruited by active search for cases at daily consultations.
Blood pressure, cholesterol, weight, tobacco habit, alcohol intake, anti-tetanus vaccination state, CR calculation at 10 years on the Framingham scale, and degree of compliance with activities were all determined at the start, at 4 years and at 8 years. Data was obtained from the clinical notes.
Total population: a 0.8 drop in CR (CI difference: 0.4-1.2), equivalent to 8.5% of the initial figure. 64.4% increase in correct anti-tetanus vaccination (CI difference: 59.9-69). Compliance with activities at the start and after eight years: pressure 100%, 71%; tobacco consumption 99.5%, 71%; cholesterol determination 89%, 64%. Initially high CR sub-group: 6.7 drop of CR at 8 years (CI difference: 4.9-8.5), equivalent to 24.8% of the initial figure.
In the total population, the CR drop found was not clinically significant, whereas in the initially high CR sub-group the drop was. There should probably be an active search made for patients with high CR and action taken on them.
主要目的:评估成年人参与预防活动与健康促进计划(PAPPS)8年后冠心病风险(CR)的变化。次要目的:确定破伤风疫苗接种水平以及患者对各项活动的依从性。
非随机分配的“前后”干预研究。
健康中心的普通医疗诊所。
429名年龄在30至65岁之间的患者(204名男性,225名女性),通过日常门诊主动筛查病例招募,进行了8年的监测。
在开始、4年和8年时分别测定血压、胆固醇、体重、吸烟习惯、酒精摄入量、破伤风疫苗接种状况、基于弗雷明汉姆量表计算的10年冠心病风险以及活动依从程度。数据来自临床记录。
总体人群:冠心病风险下降0.8(置信区间差异:0.4 - 1.2),相当于初始值的8.5%。正确接种破伤风疫苗的比例增加64.4%(置信区间差异:59.9 - 69)。开始时和8年后的活动依从情况:血压监测100%,71%;烟草消费99.5%,71%;胆固醇测定89%,64%。初始冠心病风险高的亚组:8年后冠心病风险下降6.7(置信区间差异:4.9 - 8.5),相当于初始值的24.8%。
在总体人群中,发现的冠心病风险下降在临床上无显著意义,而在初始冠心病风险高的亚组中下降具有临床意义。可能应该积极筛查冠心病风险高的患者并对其采取行动。