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一项全科医疗中降低男性心血管疾病风险项目的成效

Effectiveness of programme for reducing cardiovascular risk for men in one general practice.

作者信息

Gibbins R L, Riley M, Brimble P

出版信息

BMJ. 1993 Jun 19;306(6893):1652-6. doi: 10.1136/bmj.306.6893.1652.

Abstract

OBJECTIVES

To assess the effectiveness of a programme for reducing cardiovascular risk in men in terms of clinical measurements and perceptions of patients.

DESIGN

Collection of paired data on men attending well person clinics over three to five years. Questionnaire to determine changes in risk related habits.

SETTING

Well person clinics in rural general practice with five partners in mid-Wales.

SUBJECTS

The first 687 men seen in the clinic: analysable data obtained on 520. Initial age range 28-60 years.

MAIN OUTCOME MEASURES

Analysis of serum cholesterol concentration (mmol/l) and blood pressure (mm Hg). Changes in diet, exercise, smoking, and drinking.

RESULTS

Mean (SD) cholesterol concentration for all subjects increased from 5.8 (1.0) to 6.0 (1.0), p < 0.001. Overall percentage of ideal weight and mean systolic blood pressure also increased. Mean diastolic blood pressure was unchanged at 84 mm Hg. Professed dietary change, age, and number of visits all had significant effects on final cholesterol concentration. Those seen more often showed a significant decrease in cholesterol concentrations (in those seen more than twice mean (SD) initial value 6.7 (0.9) mmol/l v final value 6.5 (1.0) mmol/l, p < 0.001). Those over 45 years at start of study showed a significant decrease in diastolic blood pressure (mean (SD) initial value 89 (9) mm Hg v final value 86 (7) mm Hg, p < 0.001).

CONCLUSIONS

These clinics are not effective in achieving a reduction in mean cholesterol concentration or blood pressure, despite evidence that the message of reduction in risk had been successfully transmitted. Success was achieved in older patients and those in whom a definite problem was identified. Identification of high risk groups and clinical case finding with appropriate long term follow up may be more cost effective in reducing cardiovascular risk than non-specific screening of the whole population.

摘要

目的

从临床测量结果和患者认知方面评估一项降低男性心血管疾病风险计划的效果。

设计

收集在三到五年内前往健康体检诊所的男性的配对数据。通过问卷调查确定与风险相关习惯的变化。

地点

威尔士中部由五名合伙人经营的农村全科医疗健康体检诊所。

研究对象

诊所接待的前687名男性:获取了520人的可分析数据。初始年龄范围为28至60岁。

主要观察指标

分析血清胆固醇浓度(mmol/l)和血压(mmHg)。饮食、运动、吸烟和饮酒习惯的变化。

结果

所有受试者的平均(标准差)胆固醇浓度从5.8(1.0)mmol/l升至6.0(1.0)mmol/l,p<0.001。理想体重的总体百分比和平均收缩压也有所上升。平均舒张压保持不变,为84 mmHg。宣称的饮食变化、年龄和就诊次数对最终胆固醇浓度均有显著影响。就诊次数较多的患者胆固醇浓度显著降低(就诊次数超过两次者,平均(标准差)初始值为6.7(0.9)mmol/l,最终值为6.5(1.0)mmol/l,p<0.001)。研究开始时年龄超过45岁的患者舒张压显著降低(平均(标准差)初始值为89(9)mmHg,最终值为86(7)mmHg,p<0.001)。

结论

尽管有证据表明降低风险的信息已成功传达,但这些诊所未能有效降低平均胆固醇浓度或血压。在老年患者和已确诊有明确问题的患者中取得了成效。识别高危人群并进行临床病例发现以及适当的长期随访,在降低心血管疾病风险方面可能比针对全体人群的非特异性筛查更具成本效益。

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