Ahern G L, Labiner D M, Talwar D, Herring A M, Weinand M E
Department of Neurology, University of Arizona Health Sciences Center, Tucson 85724, USA.
J Clin Neurophysiol. 1995 May;12(3):285-90. doi: 10.1097/00004691-199505010-00006.
Thirty-seven subjects underwent bilateral internal carotid artery injections of amobarbital before surgery for intractable epilepsy. The electroencephalograms (EEG) of these patients were continuously monitored during these 74 procedures and were later subjected to quantitative analysis. Analysis of interhemispheric coherence in the delta, theta, alpha, and beta 1 bands was performed. Prominent changes occurred in interhemispheric coherence, which showed a precipitous drop in the first 2 min after amobarbital injection, followed by a gradual return to near baseline levels. These results suggest that interhemispheric relationships are significantly disrupted by intracarotid amobarbital injection.
