Bromham L, Clark F, McKee J J
Department of Zoology, University of Queensland, Brisbane 4072, Australia.
J Virol. 2001 Mar;75(6):3053-7. doi: 10.1128/JVI.75.6.3053-3057.2001.
Analysis of genomic and expression data allows both identification and characterization of novel retroviruses. We describe a recombinant type C murine retrovirus, similar to the Mus dunni endogenous retrovirus, with VL30-like long terminal repeats and murine leukemia virus-like coding sequences. This virus is present in multiple copies in the mouse genome and expressed in a range of mouse tissues.
对基因组和表达数据的分析有助于新型逆转录病毒的鉴定和特征描述。我们描述了一种重组C型鼠逆转录病毒,类似于邓氏小鼠内源性逆转录病毒,具有VL30样长末端重复序列和鼠白血病病毒样编码序列。这种病毒在小鼠基因组中以多拷贝形式存在,并在一系列小鼠组织中表达。