Frame I G, Cutfield J F, Poulter R T
Department of Biochemistry, University of Otago, P.O. Box 56, Dunedin, New Zealand.
Gene. 2001 Jan 24;263(1-2):219-30. doi: 10.1016/s0378-1119(00)00567-9.
The BEL group of retroelements is present in greater numbers, variety and taxonomic range than may have been thought previously. In addition to the insects, nematodes and schistosomes, BEL-like elements are present in echinoderms, urochordates, and at least two highly diverged species of fish. We describe one new full-length BEL-like element in Fugu that we call Suzu, another in Drosophila that we call Tinker, and seven new families in C. elegans. Many of the C. elegans elements have an unusual insertion at the 5' end. The previously known Roo, TRAM and Telemac are also BEL-like retrotransposons. Some BEL-like elements have captured an envelope gene, probably from other retroelements in some cases but from a phlebovirus in one case.
反转录元件的BEL家族在数量、种类和分类范围上比之前认为的更多。除了昆虫、线虫和血吸虫外，类BEL元件还存在于棘皮动物、尾索动物以及至少两种高度分化的鱼类中。我们在河豚中描述了一种新的全长类BEL元件，我们称之为铃（Suzu），在果蝇中描述了另一种，我们称之为修补匠（Tinker），并在秀丽隐杆线虫中发现了七个新家族。许多秀丽隐杆线虫元件在5'端有一个不寻常的插入。之前已知的Roo、TRAM和Telemac也是类BEL反转录转座子。一些类BEL元件捕获了一个包膜基因，在某些情况下可能来自其他反转录元件，但在一个案例中来自静脉病毒。
