Sherer D M, Abulafia O, Eliakim R
Department of Obstetrics and Gynecology, St. Luke's-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10019, USA.
Gynecol Obstet Invest. 2001;51(2):73-80. doi: 10.1159/000052897.
Pseudomyxoma peritonei is an unusual condition more common in females, in which massive amounts of mucinous ascites in conjunction with mucinous peritoneal and omental implants occur. We performed a MEDLINE search of the English-language literature from 1966 to June 2000, utilizing the key words pseudomyxoma peritonei. All case reports, series and studies regarding this condition were reviewed. Cross-referencing was also performed. The etiology and treatment of this condition are currently controversial. Most investigators agree that surgical debulking and appendectomy are adequate initial therapeutic measures. The role of intraperitoneal chemotherapy, radiotherapy or application of mucolytic therapy remains uncertain. Recent molecular genetic studies suggest the appendix as the organ of primary origin of this disease.
腹膜假黏液瘤是一种较为罕见的疾病，在女性中更为常见，其特征是出现大量黏液性腹水，并伴有黏液性腹膜和网膜种植。我们利用关键词“腹膜假黏液瘤”对1966年至2000年6月的英文文献进行了MEDLINE检索。对所有关于该疾病的病例报告、系列研究和相关研究进行了综述，并进行了交叉引用。该疾病的病因和治疗目前存在争议。大多数研究者认为手术减瘤和阑尾切除术是适当的初始治疗措施。腹膜内化疗、放疗或黏液溶解疗法的作用仍不明确。最近的分子遗传学研究表明阑尾是该疾病的原发器官。
