Kida H
Department of Disesase Control, Hokkaido University Graduate School of Veterinary Medicine.
Nihon Rinsho. 2000 Nov;58(11):2217-23.
The 1957 Asian H2N2 and 1968 Hong Kong H3N2 pandemic strains of influenza are genetic reassortants between avian viruses and human strains. Since avian viruses of any subtype can contribute genes in the generation of reassortants in pigs, none of the 15 HA and 9 NA subtypes can be ruled out as potential candidates for future pandemics. The H5N1 influenza virus transmission from domestic poultry to humans in Hong Kong in 1997 further emphasized the need to have information on influenza viruses in avian species. For the prediction and control of future pandemics, the program of global surveillance of animal influenza has been started. Influenza virus isolates from animal species should be thoroughly characterized and be provided for the use of diagnosis and vaccine preparation.
1957年的亚洲H2N2型和1968年的香港H3N2型流感大流行毒株是禽流感病毒和人流感毒株之间的基因重配体。由于任何亚型的禽流感病毒都可能在猪体内产生重配体的过程中贡献基因，因此15种血凝素（HA）亚型和9种神经氨酸酶（NA）亚型中的任何一种都不能排除是未来大流行的潜在候选毒株。1997年香港发生的H5N1型禽流感病毒从家禽传播给人类的事件进一步凸显了掌握禽类流感病毒信息的必要性。为了预测和控制未来的大流行，已经启动了动物流感全球监测计划。应该对从动物物种中分离出的流感病毒进行全面鉴定，并提供用于诊断和疫苗制备。
