Hesslinger B, Walden J, Normann C
University of Freiburg, Department of Psychiatry and Psychotherapy, Germany.
Pharmacopsychiatry. 2001 Jan;34(1):25-6. doi: 10.1055/s-2001-15190.
Catatonia is a rare but difficult-to-treat disorder. Here, we report on the case of a schizophrenic patient who developed several episodes of severe catatonia after suffering from adequately treated Lyme disease with encephalitis. The catatonic stupor was not responsive to typical neuroleptics and benzodiazepines. After the medication was changed to risperidone, there was a dramatic and persistent improvement of the patient's condition. Two relapses during the follow-up period over five years were caused by dose reductions. Risperidone might be a promising drug in the treatment of acute catatonia and in preventing further episodes.
紧张症是一种罕见但难以治疗的疾病。在此，我们报告一例精神分裂症患者的病例，该患者在接受充分治疗的莱姆病合并脑炎后出现了几次严重紧张症发作。紧张性木僵对典型的抗精神病药物和苯二氮䓬类药物无反应。在将药物改为利培酮后，患者的病情有了显著且持续的改善。在五年的随访期内，两次复发是由剂量减少引起的。利培酮可能是治疗急性紧张症和预防进一步发作的一种有前景的药物。
