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一名西班牙裔青少年未确诊的紧张型精神分裂症病例:社会决定因素在诊断中的意义以及利培酮和劳拉西泮的治疗效果

A Case of Undiagnosed Schizophrenia With Catatonia in a Hispanic Adolescent: The Significance of Social Determinants in the Diagnosis and the Efficacy of Risperidone and Lorazepam in Treatment.

作者信息

Tedesco Sarah, Gonzalez Raquel, Owusu-Antwi Philipa, Robinson Raymond E, Janusz Christopher

机构信息

Department of Psychiatry, Richmond University Medical Center, Staten Island, USA.

Department of Clinical Medicine, American University of Antigua, St. John's, ATG.

出版信息

Cureus. 2023 Jul 28;15(7):e42598. doi: 10.7759/cureus.42598. eCollection 2023 Jul.

Abstract

Catatonia is a potentially life-threatening motor dysregulation syndrome associated with various psychiatric, medical, or developmental conditions. It is not uncommon but rarely described in the pediatric population. The timely identification of catatonia is essential as the treatment approach differs from the differential diagnoses and possible underlying conditions. The social determinants of health are factors that may negatively impact psychological well-being, increase the risk and prevalence of mental disorders, and deteriorate the prognosis for those who already have them. The comprehension of social determinants of health is essential because it provides a deeper understanding of the complexity of societal structures and how they influence the lives of children and families. This case demonstrates how social determinants of health may contribute to misdiagnosis, delayed diagnosis, and an increase in the incidence of mental health disorders. We present a case report on a Hispanic adolescent with first-episode catatonia in the presence of disorganized, psychotic thoughts. The patient was successfully treated with the lorazepam challenge in conjunction with Risperidone M-Tab treatment in three days. The origin of catatonia was rooted in undiagnosed schizophrenia that had worsened over a year originating from a first-episode break that questions an untreated substance-induced psychosis: the substance is unknown, as her parents had not brought her to the emergency department at that time. The demographics of this patient have also placed her at risk for a lack of access and sociocultural aspects in the delay of treatment. Through this case report, we aim to highlight some critical points in diagnosing and managing nonmalignant catatonia in a demographically underserved minority adolescent female. This report emphasizes the need for more data about the etiology and treatment of catatonia, especially in the pediatric population.

摘要

紧张症是一种可能危及生命的运动失调综合征,与各种精神、医学或发育状况相关。它并不罕见,但在儿科人群中很少被描述。及时识别紧张症至关重要,因为其治疗方法与鉴别诊断及可能的潜在病症不同。健康的社会决定因素是可能对心理健康产生负面影响、增加精神障碍风险和患病率并使已有精神障碍者的预后恶化的因素。理解健康的社会决定因素至关重要,因为它能更深入地理解社会结构的复杂性以及它们如何影响儿童和家庭的生活。本病例展示了健康的社会决定因素如何导致误诊、诊断延迟以及精神健康障碍发病率增加。我们报告一例患有首发紧张症且伴有思维紊乱、精神病性症状的西班牙裔青少年病例。患者在三天内通过劳拉西泮激发试验联合利培酮口崩片治疗成功康复。紧张症的根源是未被诊断出的精神分裂症,该病自首次发作后一年来不断恶化,最初发作时疑似未治疗的物质所致精神病:物质不明,因为当时其父母未带她去急诊科。该患者的人口统计学特征也使其在治疗延迟方面面临缺乏医疗服务及社会文化因素的风险。通过本病例报告,我们旨在强调在诊断和管理人口统计学上服务不足的少数族裔青少年女性的非恶性紧张症时的一些关键点。本报告强调需要更多关于紧张症病因和治疗的数据,尤其是在儿科人群中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/839d/10460505/61065bc7f499/cureus-0015-00000042598-i01.jpg

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