与帕利哌酮治疗启动相关的紧张症。
Catatonia associated with initiating paliperidone treatment.
机构信息
Oregon Health & Science University, Department of Emergency Medicine, Oregon Poison Control Center, Portland VA.
出版信息
West J Emerg Med. 2010 May;11(2):186-8.
Abstract
We present a case of catatonia, which occurred shortly after starting a new antipsychotic, paliperidone, an active metabolite of risperidone. Catatonia may be caused by a variety of conditions, including metabolic, neurologic, psychiatric and toxic processes. Interestingly, risperidone, which has been thought to cause several cases of catatonia, has also been recommended as a potential treatment. We discuss potential mechanisms for causes of drug-induced catatonia as well as potential treatment options.
摘要
我们报告了一例因使用新型抗精神病药物帕利哌酮（利培酮的活性代谢产物）后不久而发生的紧张症。紧张症可能由多种情况引起，包括代谢、神经、精神和中毒性疾病。有趣的是，虽然曾有几例紧张症被认为是由利培酮引起的，但利培酮也被推荐为潜在的治疗药物。我们讨论了药物引起紧张症的潜在机制和潜在的治疗选择。
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