Sinclair P A, Lyness J M, King D A, Cox C, Caine E D
Laboratory of Depression and Medical Comorbidity, Program in Geriatrics and Neuropsychiatry, Department of Psychiatry, University of Rochester School of Medicine, NY, USA.
Am J Psychiatry. 2001 Mar;158(3):416-9. doi: 10.1176/appi.ajp.158.3.416.
The authors' goal was to examine whether depression is associated with overreporting of functional disability.
The subjects were 304 patients 60 years old or older who were recruited from primary care settings. Measures included examiner ratings of depression diagnosis and medical burden and self-reported and examiner-rated functional assessments. Multiple regression techniques were used to determine the independent association of depression with self-reported function after examiner-rated function was added to the analysis as a covariate.
Depression diagnosis was associated with poorer self-reported role functioning, whether the patient attributed the disability to physical or emotional causes. Depression was not independently associated with poorer self-reported physical functioning.
Clinicians and researchers should recognize that depression can confound the self-reporting and attribution of functional disability.
作者旨在研究抑郁症是否与功能残疾的过度报告相关。
研究对象为304名60岁及以上从初级保健机构招募的患者。测量指标包括检查者对抑郁症诊断和医疗负担的评分,以及自我报告和检查者评定的功能评估。在将检查者评定的功能作为协变量纳入分析后,采用多元回归技术确定抑郁症与自我报告功能之间的独立关联。
无论患者将残疾归因于身体还是情感原因,抑郁症诊断都与较差的自我报告角色功能相关。抑郁症与较差的自我报告身体功能无独立关联。
临床医生和研究人员应认识到,抑郁症会混淆功能残疾的自我报告和归因。