Barrera R, Nygard S, Sogoloff H, Groeger J, Wilson R
Department of Anesthesiology and Critical Care Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
J Crit Care. 2001 Mar;16(1):32-5. doi: 10.1053/jcrc.2001.21794.
The purpose of this study was to compare the accuracy of outcome predictions made on the day of intensive care unit (ICU) admission by critical care physicians, critical care fellows, and primary team physicians.
Fifty-nine consecutive patients admitted to a Medical-Surgical ICU were included in the study. Two ICU attending physicians and two critical care fellows, not involved in medical management, evaluated each new ICU patient at admission and after 48 to 72 hours. Altogether six ICU attendings and six fellows were involved in the study. Each investigator separately assigned probability to each patient of being discharged alive from the ICU and the hospital. On the day of admission the primary service was also asked to estimate the likelihood of successful outcome. All values are expressed in percentiles. Statistical analysis was performed by a logistic regression procedure with a binary outcome. Data are presented as mean +/- SD.
Fifty-nine patients were surveyed. Twenty-six (44%) patients died in the ICU, 3 (5%) died in the hospital wards, and 30 (51%) were discharged alive from the hospital. ICU attendings most reliably and accurately estimated patient outcome on admission compared with critical care fellows and primary team physicians. ICU attendings were more consistent than ICU fellows at predicting outcome at 48 and 72 hours. Clinical predictions were better for patients at the extremes of disease severity, and the accuracy of predictions in these patients was highest. Accuracy was diminished in patients with moderate compromise of clinical status.
ICU attendings predicted most accurately and consistently the final outcome of patients, and ICU fellows estimated outcome more reliably than the primary service. For the most part, the primary service tended to overestimate the probability of favorable outcome of patients for whom ICU admission had been requested. Additionally, clinical accuracy of survival or mortality was best for those patients at the extremes of clinical compromise: this point seems to confirm the validity of using clinical judgement as a guide to restricting ICU resources for those severely compromised or mildly compromised.This study also indicates that predictions of outcome in critically ill patients made within days of admission are statistically valid but not sufficiently reliable to justify irrevocable clinical decisions at present.
本研究旨在比较重症监护医师、重症医学专科住院医师和原治疗团队医师在重症监护病房(ICU)收治当日所做预后预测的准确性。
本研究纳入了59例连续入住内科-外科ICU的患者。两名未参与医疗管理的ICU主治医师和两名重症医学专科住院医师在患者入院时以及48至72小时后对每位新入住ICU的患者进行评估。共有六名ICU主治医师和六名专科住院医师参与了该研究。每位研究者分别为每位患者从ICU和医院存活出院的可能性赋值。在入院当日,原治疗团队也被要求评估预后成功的可能性。所有数值均以百分位数表示。采用二元转归的逻辑回归程序进行统计分析。数据以均值±标准差表示。
共对59例患者进行了调查。26例(44%)患者在ICU死亡,3例(5%)在医院病房死亡,30例(51%)存活出院。与重症医学专科住院医师和原治疗团队医师相比,ICU主治医师在入院时对患者预后的估计最为可靠和准确。在预测48小时和72小时后的预后时,ICU主治医师比ICU专科住院医师更为一致。对于病情严重程度处于极端状态的患者,临床预测效果更好,且这些患者的预测准确性最高。临床状态中度受损的患者预测准确性降低。
ICU主治医师对患者的最终预后预测最为准确和一致,且ICU专科住院医师对预后的估计比原治疗团队更可靠。在很大程度上,原治疗团队倾向于高估那些被要求入住ICU患者获得良好预后的概率。此外,对于临床状态处于极端状态的患者,生存或死亡的临床预测准确性最佳:这一点似乎证实了将临床判断作为指导限制对那些严重受损或轻度受损患者使用ICU资源的有效性。本研究还表明,在入院数天内对危重症患者的预后预测在统计学上是有效的,但目前尚不足以可靠到足以证明做出不可撤销的临床决策是合理的。