Wilkes C H, Visscher M B
J Bone Joint Surg Am. 1975 Jan;57(1):49-57.
An investigation was made into some of the hemodynamic properties of bone. The parameters studied were bone marrow and medullary venous pressures. The resting level and changes in the two pressures were measured under autoperfusion and constant-flow perfusion conditions. Changes were induced either by drugs or by alteration in blood flow. Marrow pressure was measured with a new tonometric technique. A specially constructed miniature pressure transducer was utilized as the tonometer. Trauma-induced hemorrhage of the marrow was avoided. The marrow pressure was measured across an intact endosteal membrane. The pressure of the normal bone marrow and the medullary venous pressure in the anesthetized dog were nearly equal, approximately twenty millimeters of mercury and about 17 per cent of systemic blood pressure. These values were found whether measured simultaneously or separately in comparable groups of dogs under a variety of conditions. Induced changes in the two pressures produced either by changes in perfusion rate or by drugs were also nearly equal and in the same direction.
对骨的一些血液动力学特性进行了研究。所研究的参数是骨髓压和髓静脉压。在自体灌注和恒流灌注条件下测量了这两种压力的静息水平及其变化。通过药物或血流改变诱导变化。采用一种新的张力测量技术测量骨髓压。使用特制的微型压力传感器作为张力计。避免了创伤引起的骨髓出血。通过完整的骨内膜膜测量骨髓压。麻醉犬正常骨髓压和髓静脉压几乎相等，约为20毫米汞柱，约为体循环血压的17%。在各种条件下，在可比的犬组中同时或分别测量时，均得到这些值。由灌注率变化或药物引起的这两种压力的诱导变化也几乎相等且方向相同。
