Jauffret J L, Champsaur P, Robaglia-Schlupp A, Andrac-Meyer L, Magalon G
Service de chirurgie plastique réparatrice et esthétique, hôpital la Conception, 147, boulevard Baille, 13005 Marseille, France.
Ann Chir Plast Esthet. 2001 Feb;46(1):31-8.
The main criticism against fat reinjection procedures is related to whether it is possible to graft adipocytes or not. The ideal solution would be to perform biopsies a few months after the operation to check the evolution of the grafted tissue, but such an approach would be difficult to accept for our patients. To overcome this difficulty the authors have compiled all the arguments that plead in favor of adipocyte grafts when Coleman's technique is used. Peer demonstrated in animal studies that it is possible to graft fatty tissue and that more resorption occurs when the fragments are large in size. The histologic studies have shown that the different stages of Coleman's technique do not alter the viability of the adipocytes. A disorganization of the architecture of the lobules is observed, but this does not compromise the theory of adipocyte grafting. An MRI study, performed on ten patients, demonstrated that the reinjected fat cells persist several months after the procedure. These fat cells presented the same characteristics as the patient's native fat in the surrounding area. This impression was confirmed by histological analysis of the reinjected fatty tissue 18 months after the graft. Finally, the clinical results obtained on over 200 patients treated for various indications in plastic and cosmetic surgery lead us to believe that it is possible to perform grafts of fatty tissue.
对脂肪再注射手术的主要批评与是否能够移植脂肪细胞有关。理想的解决方案是在手术后几个月进行活检，以检查移植组织的演变情况，但这种方法对我们的患者来说很难接受。为了克服这一困难，作者整理了所有支持在使用科尔曼技术时进行脂肪细胞移植的论据。皮尔在动物研究中证明，移植脂肪组织是可行的，而且当碎片尺寸较大时，吸收更多。组织学研究表明，科尔曼技术的不同阶段不会改变脂肪细胞的活力。观察到小叶结构紊乱，但这并不影响脂肪细胞移植理论。对10名患者进行的一项MRI研究表明，再注射的脂肪细胞在手术后持续数月。这些脂肪细胞与周围区域患者的天然脂肪具有相同的特征。移植18个月后对再注射脂肪组织进行的组织学分析证实了这一印象。最后，对200多名因整形和美容手术的各种适应症接受治疗的患者所获得的临床结果使我们相信，进行脂肪组织移植是可行的。
