Rohrich Rod J, Sorokin Evan S, Brown Spencer A
Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas 75390-9132, USA.
Plast Reconstr Surg. 2004 Jan;113(1):391-5; discussion 396-7. doi: 10.1097/01.PRS.0000097293.56504.00.
Fat grafting is an unpredictable procedure that continues to challenge the field of plastic surgery due to irregular resorption. Applications for this procedure are broad in both reconstructive and cosmetic plastic surgery. Fat grafts are carefully obtained and manipulated to obtain better graft takes and results, yet there is no universal agreement on what constitutes an ideal methodology. The present study examines adipocyte viability from four commonly used donor sites in five subjects. No statistical differences in adipocyte viability were demonstrated among abdominal fat, thigh fat, flank fat, or knee fat donor sites that were immediately removed and untreated (p < 0.225). In addition, no differences were observed in representative tissue samples that were removed and centrifuged (thigh, p = 0.508; knee, p = 0.302; flank, p = 0.088; abdomen, p = 0.533). On the basis of these quantitative data, neither harvest location nor centrifugation demonstrated any advantage in terms of lipocyte viability. Fat tissue transfers from these common sites may be considered equal, and centrifugation does not appear to enhance immediate fat tissue viability before implantation.
脂肪移植是一种不可预测的手术，由于其吸收率不规律，一直对整形外科领域构成挑战。该手术在重建整形外科和美容整形手术中的应用都很广泛。脂肪移植需要小心获取和处理，以获得更好的移植成活率和效果，但对于什么构成理想的方法，目前尚无普遍共识。本研究检测了5名受试者4个常用供区的脂肪细胞活力。立即切除且未经处理的腹部脂肪、大腿脂肪、侧腹脂肪或膝部脂肪供区之间，脂肪细胞活力无统计学差异（p < 0.225）。此外，对切除并离心的代表性组织样本进行观察，也未发现差异（大腿，p = 0.508；膝部，p = 0.302；侧腹，p = 0.088；腹部，p = 0.533）。基于这些定量数据，就脂肪细胞活力而言，供区位置和离心处理均未显示出任何优势。来自这些常见部位的脂肪组织移植可被视为等同，并且在植入前，离心处理似乎并不会提高脂肪组织的即时活力。
