Kudel'kina N A, Molokov A L
Ter Arkh. 2001;73(1):8-12.
To study prevalence of factors of risk to develop chronic noninfectious diseases (CNID) in the population of railroad men of the West Siberia and these factors association with ischemic heart disease (IHD) and cerebrovascular disorders.
A one-stage sample epidemiological survey of CNID risk factors enrolled 10,677 railroad men of West Siberia aged 20-65 years. The risk factors were: arterial hypertension (AH), smoking, hypercholesterolemia (HCE), obesity, low physical activity (LPA), impaired flucose tolerance (IGT).
High incidence of AH, HCE, smoking, obesity, LPA, IGT as well as nutritional shift to food rich in fat was found. The results of the regression multivariate analysis show that such factors as AH, HCE and smoking are associated with and contribute much to high risk of IHD; AH, severe HCE and obesity contribute to high risk of cerebral pathology.
Further studies are needed of CNID prevalence among railroad men. Measures of primary multifactor prevention should be designed and introduced to correct the above risk factors.
研究西西伯利亚铁路职工人群中慢性非传染性疾病(CNID)发病风险因素的流行情况,以及这些因素与缺血性心脏病(IHD)和脑血管疾病的关联。
对10677名年龄在20 - 65岁的西西伯利亚铁路职工进行了一项关于CNID风险因素的单阶段抽样流行病学调查。风险因素包括:动脉高血压(AH)、吸烟、高胆固醇血症(HCE)、肥胖、低体力活动(LPA)、糖耐量受损(IGT)。
发现AH、HCE、吸烟、肥胖、LPA、IGT的发病率较高,以及饮食向富含脂肪的食物转变。回归多变量分析结果表明,AH、HCE和吸烟等因素与IHD的高风险相关且起很大作用;AH、重度HCE和肥胖导致脑部病变的高风险。
需要进一步研究铁路职工中CNID的流行情况。应设计并引入初级多因素预防措施以纠正上述风险因素。