Pietrzak-Nowacka Maria, Safranow Krzysztof, Rulkowska Halina, Brzosko Marek, Domański Leszek, Dutkiewicz Grazyna, Ławniczak Małgorzata, Płońska Edyta, Szmatłoch Eugeniusz
Klinika Nefrologii, Transplantologii i Chorób Wewnetrznych Pomorskiej Akademii Medycznej, Szczecin.
Ann Acad Med Stetin. 2006;52(2):71-7.
The aim of this study was to perform a retrospective analysis of selected risk factors and their variability in a 10 years period of observation in patients with ischemic heart disease (IHD).
We reviewed 5219 questionares of patients hospitalized at internal wards of the Internal Medicine Institute of the Pomeranian Medical University in Szczecin. Among the participants 1709 were females with mean age 56.3 +/- 7.1 and 3510 males with mean age 54.46 +/- 7.96. Multivariate logistic regression analysis of the relationship between the: analysed risk factors and the hospitalization year, age and sex of patients was used.
Among all risk factors, cigarette smoking appeared most frequently (43.93% of patients) followed by arterial hypertension (32.90%), lipid disturbances (25.78%), obesity (16.26%), type 2 diabetes (13.79%), family history of IHD (8.46%), impaired glucose tolerance (5.8%), hyperuricaemia (3.62%) and type 1 diabetes (1.1%). Cigarette smoking and hyperuricaemia appeared markedly more often in men in comparison to women (p < 0.0002) in whom arterial hypertension and obesity significantly dominated (p < 0.0001).
During the 10-years period of observation a significant raise of arterial hypertension, dyslipidemia, hyperuricaemia, type 2 diabetes mellitus and impaired glucose tolerance was found. Hovever, some positive changes such as a decrease in number of cigarette smokers and obesity among women were detected. In conclusion, the results of our study show that between 1983 and 1992 there was a domination of negative changes among the IHD risk factors. This was more pronounced in the studied group of females in comparison to males.
本研究旨在对缺血性心脏病（IHD）患者进行为期10年的观察，对选定的危险因素及其变异性进行回顾性分析。
我们回顾了什切青波美拉尼亚医科大学内科研究所内科病房住院患者的5219份问卷。参与者中，1709名女性的平均年龄为56.3±7.1岁，3510名男性的平均年龄为54.46±7.96岁。采用多因素logistic回归分析所分析的危险因素与患者住院年份、年龄和性别的关系。
在所有危险因素中，吸烟最为常见（43.93%的患者），其次是动脉高血压（32.90%）、血脂紊乱（25.78%）、肥胖（16.26%）、2型糖尿病（13.79%）、IHD家族史（8.46%）、糖耐量受损（5.8%）、高尿酸血症（3.62%）和1型糖尿病（1.1%）。与女性相比，男性吸烟和高尿酸血症更为常见（p<0.0002），而女性中动脉高血压和肥胖更为显著（p<0.0001）。
在10年的观察期内，发现动脉高血压、血脂异常、高尿酸血症、2型糖尿病和糖耐量受损显著增加。然而，也检测到一些积极变化，如女性吸烟人数和肥胖人数减少。总之，我们的研究结果表明，1983年至1992年间，IHD危险因素中负面变化占主导地位。与男性相比，在研究的女性组中更为明显。
