• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[局部麻醉药浸润手术切口用于腰椎间盘突出症手术患者术后镇痛。罗哌卡因与布比卡因的对比研究]

[Infiltration of the surgical wound with local anesthetic for postoperative analgesia in patients operated on for lumbar disc herniation. Comparative study of ropivacaine and bupivacaine].

作者信息

Hernández-Palazón J, Tortosa Serrano J A, Burguillos López S, Molero Molero E

机构信息

Servicio de Anestesiología y Reanimación, Hospital Universitario Virgen de la Arrixaca, Murcia.

出版信息

Rev Esp Anestesiol Reanim. 2001 Jan;48(1):17-20.

PMID:11234601
Abstract

OBJECTIVE

To assess and compare the analgesic efficacy of infiltrating the wound with ropivacaine or bupivacaine for postoperative pain after lumbar disk repair.

PATIENTS AND METHODS

A prospective, randomized double blind study of 45 patients undergoing elective surgery for herniated lumbar disk repair under general anesthesia. Before the surgical wound was closed, the paraspinal musculature and subcutaneous tissue were infused with 30 ml of 0.25% ropivacaine in group I (n = 15), 30 ml of 0.25% bupivacaine in group II (n = 15) or 30 ml of saline solution in group III (n = 15). Ketorolac for supplementary postoperative analgesia was made available through a patient-controlled intravenous system. We analyzed the degree of pain on a visual analog scale and level of pain relief on a simple descriptive scale.

RESULTS

No significant differences in demographic data, duration of surgery or amount of intraoperative fentanyl administered were observed among the groups. Mean time until the first request for analgesia was significantly longer in group II than in either groups I or III (164 +/- 53 min versus 68 +/- 31 and 38 +/- 14 min, respectively). Significantly less ketorolac was used in groups I and II than in group III (58 +/- 20 and 59 +/- 21 mg versus 118 +/- 32 mg). The mean scores on the visual analog scale were similar in all three groups.

CONCLUSIONS

In this study, infiltration of the surgical wound with 0.25% bupivacaine or 0.25% ropivacaine was similarly effective for treatment of pain after lumbar disk laminectomy.

摘要

目的

评估并比较罗哌卡因或布比卡因伤口浸润用于腰椎间盘修复术后疼痛的镇痛效果。

患者与方法

一项前瞻性、随机双盲研究,纳入45例在全身麻醉下接受择期腰椎间盘突出症修复手术的患者。在手术切口关闭前,I组(n = 15)的椎旁肌肉组织和皮下组织注入30 ml 0.25%罗哌卡因,II组(n = 15)注入30 ml 0.25%布比卡因,III组(n = 15)注入30 ml生理盐水。通过患者自控静脉系统提供酮咯酸用于术后补充镇痛。我们采用视觉模拟量表分析疼痛程度,采用简单描述性量表分析疼痛缓解程度。

结果

各组间在人口统计学数据、手术时长或术中芬太尼用量方面未观察到显著差异。II组首次要求镇痛的平均时间显著长于I组和III组(分别为164±53分钟、68±31分钟和38±14分钟)。I组和II组使用的酮咯酸显著少于III组(分别为58±20毫克、59±21毫克和118±32毫克)。三组视觉模拟量表的平均评分相似。

结论

在本研究中,0.25%布比卡因或0.25%罗哌卡因伤口浸润用于腰椎间盘切除术后疼痛治疗的效果相似。

相似文献

1
[Infiltration of the surgical wound with local anesthetic for postoperative analgesia in patients operated on for lumbar disc herniation. Comparative study of ropivacaine and bupivacaine].[局部麻醉药浸润手术切口用于腰椎间盘突出症手术患者术后镇痛。罗哌卡因与布比卡因的对比研究]
Rev Esp Anestesiol Reanim. 2001 Jan;48(1):17-20.
2
Local infiltration analgesia followed by continuous infusion of local anesthetic solution for total hip arthroplasty: a prospective, randomized, double-blind, placebo-controlled study.局部浸润镇痛联合局部麻醉持续输注在全髋关节置换术中的应用:一项前瞻性、随机、双盲、安慰剂对照研究。
J Bone Joint Surg Am. 2013 Nov 6;95(21):1935-41. doi: 10.2106/JBJS.L.00477.
3
Comparison of ropivacaine with and without fentanyl vs bupivacaine with fentanyl for postoperative epidural analgesia in bilateral total knee replacement surgery.比较罗哌卡因联合或不联合芬太尼与布比卡因联合芬太尼用于双侧全膝关节置换术后硬膜外镇痛。
J Clin Anesth. 2017 Feb;37:7-13. doi: 10.1016/j.jclinane.2016.08.020. Epub 2016 Dec 22.
4
[Bupivacaine in continuous epidural infusion using a portable mechanical devise for postoperative analgesia after surgery for hernia of the lumbar disk].[使用便携式机械装置持续硬膜外输注布比卡因用于腰椎间盘疝修补术后镇痛]
Rev Esp Anestesiol Reanim. 2001 Feb;48(2):59-64.
5
Postoperative narcotic requirement after microscopic lumbar discectomy is not affected by intraoperative ketorolac or bupivacaine.显微镜下腰椎间盘切除术后的术后麻醉药物需求量不受术中使用酮咯酸或布比卡因的影响。
Spine (Phila Pa 1976). 2001 Mar 15;26(6):658-61. doi: 10.1097/00007632-200103150-00021.
6
Perioperative use of corticosteroid and bupivacaine combination in lumbar disc surgery: a randomized controlled trial.腰椎间盘手术中皮质类固醇与布比卡因联合用药的围手术期应用:一项随机对照试验。
Spine (Phila Pa 1976). 2002 Feb 15;27(4):343-6. doi: 10.1097/00007632-200202150-00003.
7
Patient supplemented epidural analgesia after major abdominal surgery with bupivacaine/fentanyl or ropivacaine/fentanyl.腹部大手术后患者采用布比卡因/芬太尼或罗哌卡因/芬太尼进行硬膜外镇痛补充。
Can J Anaesth. 2000 Jan;47(1):27-32. doi: 10.1007/BF03020727.
8
Local wound infiltration with bupivacaine in lumbar laminectomy.
Surg Neurol. 1997 Feb;47(2):120-2; discussion 122-3. doi: 10.1016/s0090-3019(96)00255-8.
9
Efficacy of continuous wound infiltration of local anesthetic for pain relief after gynecologic laparoscopy.局部麻醉药持续伤口浸润在妇科腹腔镜术后止痛中的疗效。
Int J Gynaecol Obstet. 2014 Mar;124(3):212-5. doi: 10.1016/j.ijgo.2013.08.019. Epub 2013 Nov 23.
10
Preincisional local infiltration of levobupivacaine vs ropivacaine for pain control after laparoscopic cholecystectomy.左旋布比卡因与罗哌卡因术前局部浸润用于腹腔镜胆囊切除术后的疼痛控制
Surg Endosc. 2003 Dec;17(12):1961-4. doi: 10.1007/s00464-002-9256-1. Epub 2003 Oct 28.

引用本文的文献

1
Wound Infiltration and Instillation Technique for Postoperative Analgesia Using Bupivacaine in Patients Undergoing Lumbar Spine Surgeries.布比卡因用于腰椎手术患者术后镇痛的伤口浸润与滴注技术
Cureus. 2022 Mar 28;14(3):e23592. doi: 10.7759/cureus.23592. eCollection 2022 Mar.
2
Efficacy of Periarticular Cocktail Injection in Rheumatoid Patients Undergoing Total Knee Replacement.关节周围鸡尾酒注射在类风湿性关节炎患者全膝关节置换术中的疗效
Indian J Orthop. 2020 Aug 20;54(6):811-822. doi: 10.1007/s43465-020-00230-3. eCollection 2020 Nov.
3
Efficacy and safety of epidural steroid injection following discectomy for patients with lumbar disc herniation: A protocol.
腰椎间盘突出症患者椎间盘切除术后硬膜外注射类固醇的疗效与安全性:一项方案。
Medicine (Baltimore). 2020 Jul 17;99(29):e21220. doi: 10.1097/MD.0000000000021220.
4
Effectiveness of intraoperative periarticular cocktail injection for pain control and knee motion recovery after total knee replacement.关节周围鸡尾酒式术中注射对全膝关节置换术后疼痛控制及膝关节活动恢复的有效性
Arthroplast Today. 2019 Jul 12;5(3):320-324. doi: 10.1016/j.artd.2019.05.004. eCollection 2019 Sep.
5
Study of Wound Instillation Technique for Effective Postoperative Analgesia using Ropivacaine in Lumbar Spine Surgery.罗哌卡因伤口滴注技术用于腰椎手术有效术后镇痛的研究
Anesth Essays Res. 2018 Jul-Sep;12(3):685-689. doi: 10.4103/aer.AER_87_18.
6
Effect of epidural levobupivacaine with or without dexamethasone soaked in gelfoam for postoperative analgesia after lumbar laminectomy: A double blind, randomised, controlled trial.腰椎板切除术后使用含或不含地塞米松的左旋布比卡因浸泡明胶海绵进行硬膜外镇痛的效果:一项双盲、随机、对照试验。
Indian J Anaesth. 2018 Jul;62(7):509-515. doi: 10.4103/ija.IJA_128_18.
7
Comparison of Bupivacaine Plus Magnesium Sulfate and Ropivacaine Plus Magnesium Sulfate Infiltration for Postoperative Analgesia in Patients Undergoing Lumbar Laminectomy: A Randomized Double-blinded Study.布比卡因加硫酸镁与罗哌卡因加硫酸镁浸润用于腰椎椎板切除术后患者镇痛的比较:一项随机双盲研究
Anesth Essays Res. 2017 Jul-Sep;11(3):686-691. doi: 10.4103/0259-1162.206859.
8
Periarticular injection with bupivacaine for postoperative pain control in total knee replacement: a prospective randomized double-blind controlled trial.布比卡因关节周围注射用于全膝关节置换术后疼痛控制:一项前瞻性随机双盲对照试验。
Adv Orthop. 2012;2012:107309. doi: 10.1155/2012/107309. Epub 2012 Oct 22.