Onofrio B M
J Neurosurg. 1975 Apr;42(4):384-8. doi: 10.3171/jns.1975.42.4.0384.
The author presents an evaluation of 72 patients given intradiscal chymopapain as the treatment for symptoms related to ruptured intervertebral disc. The rationale, criteria for patient selection, risks, and results are described. The author believes thatt this early follow-up suggests tha chymopapain may have a place in the treatment of symptomatic disc protrusions and extrusions.
作者对72例接受椎间盘内注射木瓜凝乳蛋白酶治疗椎间盘破裂相关症状的患者进行了评估。文中描述了治疗原理、患者选择标准、风险及结果。作者认为,这一早期随访表明木瓜凝乳蛋白酶在有症状的椎间盘突出和脱出治疗中可能占有一席之地。