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向椎间盘内注射木瓜凝乳蛋白酶。72例椎间盘疾病症状患者的初步报告。

Injection of cymopapain into intervertebral discs. Preliminary report on 72 patients with symptoms of disc disease.

作者信息

Onofrio B M

出版信息

J Neurosurg. 1975 Apr;42(4):384-8. doi: 10.3171/jns.1975.42.4.0384.

DOI:10.3171/jns.1975.42.4.0384
PMID:1123656
Abstract

The author presents an evaluation of 72 patients given intradiscal chymopapain as the treatment for symptoms related to ruptured intervertebral disc. The rationale, criteria for patient selection, risks, and results are described. The author believes thatt this early follow-up suggests tha chymopapain may have a place in the treatment of symptomatic disc protrusions and extrusions.

摘要

作者对72例接受椎间盘内注射木瓜凝乳蛋白酶治疗椎间盘破裂相关症状的患者进行了评估。文中描述了治疗原理、患者选择标准、风险及结果。作者认为，这一早期随访表明木瓜凝乳蛋白酶在有症状的椎间盘突出和脱出治疗中可能占有一席之地。

相似文献

1
Injection of cymopapain into intervertebral discs. Preliminary report on 72 patients with symptoms of disc disease.向椎间盘内注射木瓜凝乳蛋白酶。72例椎间盘疾病症状患者的初步报告。
J Neurosurg. 1975 Apr;42(4):384-8. doi: 10.3171/jns.1975.42.4.0384.
2
Treatment of intervertebral disc prolapse by intradiscal injection of chymopapain.椎间盘内注射木瓜凝乳蛋白酶治疗椎间盘突出症。
Med J Aust. 1985 Apr 15;142(8):431-4. doi: 10.5694/j.1326-5377.1985.tb113441.x.
3
Chemonucleolysis with chymopapain.木瓜凝乳蛋白酶化学髓核溶解术。
Hosp Pract (Off Ed). 1984 Feb;19(2):123-4, 126. doi: 10.1080/21548331.1984.11702749.
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Chymopapain for the treatment of intervertebral disc herniation. A preliminary report of a double-blind study.
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Chymopapain for the treatment of intervertebral disc herniation. The final report of a double-blind study.
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Chymopapain in the treatment of ruptured lumbar discs. Preliminary experience in 48 patients.木瓜凝乳蛋白酶治疗腰椎间盘破裂。48例患者的初步经验。
J Neurol Neurosurg Psychiatry. 1976 May;39(5):508-13. doi: 10.1136/jnnp.39.5.508.
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Mechanism of action of chymopapain in ruptured lumbar disc disease.木瓜凝乳蛋白酶在破裂型腰椎间盘疾病中的作用机制
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Double-blind evaluation of intradiscal chymopapain for herniated lumbar discs. Early results.
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Comparison of intervertebral disc disease treatment by chymopapain injection and open surgery.
J Neurosurg. 1975 Apr;42(4):397-400. doi: 10.3171/jns.1975.42.4.0397.
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Chymopapain chemonucleolysis. A preliminary report.木瓜凝乳蛋白酶化学髓核溶解术。初步报告。
Spine (Phila Pa 1976). 1980 Jul-Aug;5(4):380-4. doi: 10.1097/00007632-198007000-00012.

引用本文的文献

1
Sciatica caused by disc herniation: Why is Chymopapain Chemonucleolysis denied to our patients?椎间盘突出引起的坐骨神经痛：为何不给我们的患者使用木瓜凝乳蛋白酶化学髓核溶解术？
Int J Spine Surg. 2016 Dec 31;10:44. doi: 10.14444/3044. eCollection 2016.
2
Treatment of lumbo-ischialgias of different origins by intradiscal injection of chymopapain (discolysis). Analysis of literature and personal experiences.木瓜凝乳蛋白酶椎间盘内注射治疗（椎间盘溶解术）不同病因的腰腿痛。文献分析与个人经验
Acta Neurochir (Wien). 1982;61(1-3):73-88. doi: 10.1007/BF01740073.
3
Chemonucleolysis of lumbar intervertebral disc prolapse with chymopapain: outcome after 1 year.
木瓜凝乳蛋白酶用于腰椎间盘突出症的化学髓核溶解术：1年后的结果
Clin Rheumatol. 1987 Mar;6(1):42-9. doi: 10.1007/BF02200999.
4
Chymopapain in the treatment of ruptured lumbar discs. Preliminary experience in 48 patients.木瓜凝乳蛋白酶治疗腰椎间盘破裂。48例患者的初步经验。
J Neurol Neurosurg Psychiatry. 1976 May;39(5):508-13. doi: 10.1136/jnnp.39.5.508.