Wang F, Frisbie J H, Klein M A
Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Boston, MA, USA.
Arch Phys Med Rehabil. 2001 Feb;82(2):260-1. doi: 10.1053/apmr.2001.16341.
Clinically indicated endoscopic examinations of 56 patients with spinal cord injury (SCI) (31 for bleeding) were performed over a 3-year period, of which 3 (6%) showed solitary rectal ulcer syndrome (SRUS). The presentation was rectal bleeding or mucoid discharge. The endoscopic appearance was multiple pseudopolyps and occasional mucosal ulcers extending proximally 8 to 40cm from the anus. Mucosal biopsy specimens showed distorted mucosal glands and displaced smooth muscle fibers wrapping around the glands, the hallmark of SRUS. The affected patients had routinely used suppositories and digital stimulation for bowel care and had been paralyzed 7 to 50 years. None had rectal prolapse. These cases show that SRUS (colitis cystica profunda) can be found among patients with SCI.
在3年期间，对56例脊髓损伤（SCI）患者（31例因出血）进行了临床指征的内镜检查，其中3例（6%）表现为孤立性直肠溃疡综合征（SRUS）。表现为直肠出血或黏液样分泌物。内镜检查可见多个假息肉，偶尔可见距肛门近端8至40厘米处的黏膜溃疡。黏膜活检标本显示黏膜腺体扭曲，平滑肌纤维移位并包裹腺体，这是SRUS的特征。受影响的患者常规使用栓剂和手指刺激进行肠道护理，瘫痪时间为7至50年。均无直肠脱垂。这些病例表明，SCI患者中可发现SRUS（深部囊性结肠炎）。
