Malik A K, Bhaskar K V, Kochhar R, Bhasin D K, Singh K, Mehta S K, Datta B N
Department of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Indian J Pathol Microbiol. 1990 Jul;33(3):216-20.
Histological analysis of 33 rectal biopsies from 26 patients of solitary ulcer syndrome (SUS) of rectum was undertaken. Fibrous obliteration and smooth muscle extension into the lamina propria were the characteristic and most constant findings. The limitation of the biopsy procedure in procuring deeper tissue made the detection of colitis cystica profunda rare in our study. A combination of fibrosis of the lamina propria, superficial mucosal ulceration, muscularis mucosae hypertrophy and submucosal fibrosis, along with the clinical suspicion should clinch the diagnosis of SUS.
对26例直肠孤立性溃疡综合征（SUS）患者的33份直肠活检标本进行了组织学分析。纤维性闭塞以及平滑肌向固有层延伸是其特征性且最常见的表现。在我们的研究中，活检操作在获取更深层组织方面的局限性使得深部囊性结肠炎的检出很少见。固有层纤维化、浅表黏膜溃疡、黏膜肌层肥厚和黏膜下纤维化，再加上临床怀疑，应可确诊SUS。
