Solitary rectal ulcer syndrome and colitis cystica profunda--a clinico-pathological review.

Twenty cases of solitary rectal ulcer syndrome (SRUS) and three cases of colitis cystica profunda (CCP) diagnosed between 1985 to 1990 were studied retrospectively. Clinical features, sigmoidoscopic findings and histopathology of the above lesions were reviewed. Haematoxylin and Eosin, Masson's Trichome, and high iron diamine Alcian blue staining was done in all the cases. Histopathologic examination helps in diagnosing the benign condition of the rectum viz. SRUS and CCP which are considered malignant clinically. Since an overlap of histopathological features were seen in SRUS and CCP, both can be considered as one entity, which has been highlighted in our study. Fibromuscular obliteration of lamina propria is the hallmark of the lesion.