Gantenbein C, Seiter S, Weik R, Reinhold U, Ruprecht K W, Tilgen W
Département d'ophtalmologie des hôpitaux universitaires de la Sarre, Homburg/Sarre Allemangne.
J Fr Ophtalmol. 2001 Jan;24(1):45-8.
Generalized essential telangiectasia is a rare skin disorder characterized by the development of dilated venules beginning at the lower extremities and progressively spreading out to the rest of the body. It is not related to any known affection and is therefore considered to be essential. The condition tends to affect mostly women in their midthirties. We report the case of a 49-year-old healthy man worried by the progressive extension of dilated vessels on the conjunctivae of both eyes and the progressive worsening at the condition over the last five years. On clinical examination he presented also telangiectasies on both arms and legs which had also grown worse over the last five years. All further investigations and complementary examinations showed no disease. A cutaneous biopsy showed dilated venules in the superior dermis supporting the diagnosis of telangiectases. Several differential diagnoses are discussed. With confirmation of the clinical diagnosis we started treatment with oral tetracycline. Because of the poor response we stopped treatment after a period of three months.
泛发性特发性毛细血管扩张症是一种罕见的皮肤疾病，其特征是从小腿开始出现扩张的小静脉，并逐渐蔓延至身体其他部位。它与任何已知疾病无关，因此被认为是原发性的。这种疾病往往主要影响三十多岁的女性。我们报告了一例49岁健康男性的病例，他因双眼结膜上扩张血管的逐渐扩展以及在过去五年中病情的逐渐恶化而担忧。临床检查发现他的双臂和双腿也有毛细血管扩张，在过去五年中也有所加重。所有进一步的检查和辅助检查均未发现疾病。皮肤活检显示真皮上层有扩张的小静脉，支持毛细血管扩张症的诊断。文中讨论了几种鉴别诊断。在确诊临床诊断后，我们开始用口服四环素进行治疗。由于效果不佳，三个月后我们停止了治疗。
