Monteagudo B, Pérez-Valcárcel J, Ramírez-Santos A, Cabanillas M, Suárez-Amor O
Complejo Hospitalario Arquitecto Marcide-Novoa Santos, Ferrol, La Coruña, España.
Actas Dermosifiliogr. 2010 Jun;101(5):444-7.
Cutaneous collagenous vasculopathy is an idiopathic microangiopathy first described in 2000 by Salama and Rosenthal.It must not be confused with generalized essential telangiectasia. To date, all patients have been white men over the age of 50 years, most of whom had multiple pathologies, were taking multiple drugs, and had no family history of similar conditions or hemorrhagic disorders. The disease is characterized by the development of various numbers of telangiectases on the limbs, lower abdomen, chest, or back, with no involvement of the mucosas or nail bed. Histopathology shows dilated superficial cutaneous vessels with perivascular deposits of periodic acid-Schiff diastase-positive, eosinophilic hyaline material that exhibits positive immunoreactivity to collagen IV. We report a new case in a 68-year-old man with symmetrically distributed telangiectases on his forearms, lower abdomen, posterior thighs, lower legs, and dorsum of the feet.
皮肤胶原性血管病是一种特发性微血管病，于2000年由萨拉马和罗森塔尔首次描述。它绝不能与泛发性特发性毛细血管扩张症相混淆。迄今为止，所有患者均为50岁以上的白人男性，其中大多数人患有多种疾病，正在服用多种药物，且无类似疾病或出血性疾病的家族史。该病的特征是在四肢、下腹部、胸部或背部出现数量不等的毛细血管扩张，黏膜或甲床未受累。组织病理学显示浅表皮肤血管扩张，血管周围有过碘酸希夫淀粉酶阳性、嗜酸性透明物质沉积，对IV型胶原呈阳性免疫反应。我们报告一例68岁男性新病例，其前臂、下腹部、大腿后部、小腿和足背有对称分布的毛细血管扩张。
