Nagler R M, Reznick A Z
Dept. of Oral and Maxillofacial Surgery, Salivary Clinic and Oral Biochemistry Laboratory, Rambam Medical Center, Haifa.
Harefuah. 2001 Jan;140(1):12-5, 87.
Saliva is the first biological medium to come in contact with materials entering the body through the oral cavity. These materials are contained in food and drink (or inhaled as volatile ingredients). Accordingly, saliva contains various defense mechanisms which have been thoroughly investigated. They include immunological and enzymatic systems aimed at pathological microorganisms. Saliva also can protect the mucosa against mechanical insults and when required, promote its healing via agents such as the epidermal growth factor. Another defense mechanism in saliva which has been gaining increased attention and seems to be of paramount importance is its antioxidant system. We discuss both the molecular and enzymatic components of the salivary antioxidant system in respect to mixed, parotid, submandibular and sublingual saliva and under various physiological conditions of secretion.
唾液是第一种与通过口腔进入人体的物质接触的生物介质。这些物质存在于食物和饮料中（或作为挥发性成分被吸入）。因此，唾液含有各种已被深入研究的防御机制。它们包括针对病原微生物的免疫和酶系统。唾液还可以保护黏膜免受机械损伤，并在需要时通过表皮生长因子等物质促进其愈合。唾液中另一种越来越受到关注且似乎至关重要的防御机制是其抗氧化系统。我们将讨论唾液抗氧化系统的分子和酶成分，涉及混合唾液、腮腺唾液、颌下唾液和舌下唾液，以及在各种不同分泌生理条件下的情况。
