Liu B, Spira M, Xu Z, Ozgentas E, Shenaq S M
Institute of Occupational Medicine, Chinese Academy of Preventive Medicine, Beijing 100050.
Chin Med Sci J. 1997 Mar;12(1):26-31.
This study compares the persistence and histological characteristics of gut suture with those of human amnion collagen, bovine collagen, and Vicryl suture implants in rats. Gut suture and human amnion collagen more resembled living tissue than did bovine collagen and were characterized by their cellularity and the presence of numerous capillaries. The Vicryl suture implants were quickly absorbed. Picrosirius polarization revealed the synthesis of host collagen by rat fibroblasts which immigrated into the gut suture and human amnion collagen implants. The authors suggest the potential of gut suture as a soft tissue substitute to improve linear skin contour deficits.
本研究比较了肠缝线与人羊膜胶原蛋白、牛胶原蛋白及薇乔缝线植入大鼠体内后的持久性和组织学特征。与牛胶原蛋白相比，肠缝线与人羊膜胶原蛋白更类似于活体组织，其特征在于细胞性以及存在大量毛细血管。薇乔缝线植入物很快被吸收。天狼星红偏振显示，迁移至肠缝线和人羊膜胶原蛋白植入物中的大鼠成纤维细胞合成了宿主胶原蛋白。作者认为肠缝线作为软组织替代物改善线性皮肤轮廓缺损具有潜力。
