Hayashi S, Jinbo T, Iguchi K, Shimizu M, Shimada T, Nomura M, Ishida Y, Yamamoto S
Laboratory of Immunology, Faculty of Environmental and Health Sciences, Azabu University, Sagamihara, Kanagawa, Japan.
Vet Res Commun. 2001 Feb;25(2):117-26. doi: 10.1023/a:1006404902214.
The concentrations of C-reactive protein (CRP) and alpha1-acid glycoprotein (AAG) were evaluated in 1-, 3- and 18-month-old dogs (four of each age) that had been inoculated with turpentine oil. The CRP and AAG in 3-month-old and younger dogs subjected to surgery or inoculated with either Staphylococcus aureus or a viral vaccine were also evaluated. The average CRP concentration in the sera peaked 2 days after inoculation of turpentine oil. The peak CRP concentrations in 3- and 18-month-old dogs were significantly (p < 0.05) greater than those in 1-month-old dogs. The average AAG concentration in the sera peaked 4 days after inoculation of turpentine oil. No significant difference was found in AAG concentrations between any of the age groups. When experimentally inoculated with S. aureus or subjected to oophorohysterectomy, the CRP and AAG concentrations increased in 3-month-old dogs, but they increased little in 1-month-old dogs. The CRP and AAG in dogs inoculated with the viral vaccine did not increase. In dogs with fractures or subjected to percutaneous gastrostomy, the CRP and AAG concentrations correlated with the condition of dogs.
对接种松节油的1月龄、3月龄和18月龄犬（每个年龄组4只）的C反应蛋白（CRP）和α1-酸性糖蛋白（AAG）浓度进行了评估。还评估了接受手术或接种金黄色葡萄球菌或病毒疫苗的3月龄及以下犬的CRP和AAG。血清中CRP平均浓度在接种松节油后2天达到峰值。3月龄和18月龄犬的CRP峰值浓度显著高于1月龄犬（p<0.05）。血清中AAG平均浓度在接种松节油后4天达到峰值。各年龄组之间的AAG浓度未发现显著差异。当3月龄犬经实验接种金黄色葡萄球菌或接受卵巢子宫切除术后，CRP和AAG浓度升高，但1月龄犬升高幅度较小。接种病毒疫苗的犬的CRP和AAG未升高。在患有骨折或接受经皮胃造瘘术的犬中，CRP和AAG浓度与犬的病情相关。
